A wide variety of doctoral projects are available for students applying to the NDM. These are open to students on funded programmes (including NDM Prize Studentships, the NIH-Oxford-Cambridge Scholars Programme and other funded programmes) and to direct applicants.
| DPhil Project | Principal Investigator | Category |
|---|---|---|
| A systems approach investigation of the brain response to hypoxia in cerebral malaria (reference number 184) View project | Casals-Pascual, ClimentView profile | Tropical Medicine & Global Health |
| Acute Stroke Program – identification of neuroprotective strategies (reference number 166) View project | Buchan, AlastairView profile | Molecular & Cell Biology |
| Adiposity, physical activity, metabolic factors and cardiovascular risk among 0.5 million adults in the Kadoorie Biobank Study (reference number 124) View project | Chen, ZhengmingView profile | Clinical Trials & Epidemiology |
| Analysis of KLRB1+/KLRC1+ cells in human viral and inflammatory disease (reference number 180) View project | Klenerman, PaulView profile | Immunology |
| Analysis of next-generation sequencing data for comparative genomics (reference number 222) View project | Copley, RichardView profile | Bioinformatics & Statistics |
| Assessing T cell immunity and cross reactivity in HCV genotype-3 infection (reference number 156) View project | Barnes, EllieView profile | Immunology |
| Autophagy and antigen presentation in vivo (reference number 209) View project | Simon, Anna Katharina (Katja)View profile | Immunology |
| Characterisation of Rcalc1, an ENU mouse model for kidney stone disease (reference number 20) View project | Thakker, RajeshView profile | Endocrinology & Metabolic Medicine |
| Characterisation of the immune response in AIDS (reference number 153) View project | Frater, JohnView profile | Immunology |
| Characterization of MINA function in normal physiology and cancer (reference number 150) View project | Ratcliffe, PeterView profile | Molecular & Cell Biology |
| Chromatin conformation and epigenetic regulation of gene expression (reference number 218) View project | Goding, ColinView profile | Cancer |
| Chromosome organisation and nuclear architecture in neuronal cells. (reference number 206) View project | Volpi, EmanuelaView profile | Genetics & Genomics |
| Chronodisruption, endocrine modulation and chronic disease: Investigating the health consequences of a 24-hour society (reference number 236) View project | Travis, RuthView profile | Clinical Trials & Epidemiology |
| Computational analysis of evolving metazoan enhancers: the NF-kB driven transcriptional response during inflammation (reference number 110) View project | Copley, RichardView profile | Bioinformatics & Statistics |
| Control of venous specification and differentiation during the development of the blood vascular system (reference number 210) View project | De Val, SarahView profile | Molecular & Cell Biology |
| Controlling DNA repair by small-molecule inhibitors of human DNA helicases. (reference number 193) View project | Gileadi, OpherView profile | Protein Science & Structural Biology |
| Controlling malaria through manipulating iron availability to Plasmodium (reference number 192) View project | Drakesmith, Alexander HalView profile | Immunology |
| Cross-talk between innate and adaptive immune responses to optimize the expansion of tumour specific T cells (reference number 91) View project | Cerundolo, VincenzoView profile | Immunology |
| Crosstalk between the Wnt and p53 signalling pathways and their effects on tumour metastasis (reference number 62) View project | Lu, XinView profile | Cancer |
| Data visualisation and mining tools for a human protein kinase chemical and structural biology data resource (reference number 196) View project | Marsden, BrianView profile | Protein Science & Structural Biology |
| Designing and Testing More Potent Vaccines (reference number 165) View project | Hill, AdrianView profile | Tropical Medicine & Global Health |
| Determinants of human-to-mosquito transmission of dengue viruses (reference number 205) View project | Simmons, CameronView profile | Tropical Medicine & Global Health |
| Determining the Neurocognitive Dysfunction in SCD Children (reference number 221) View project | Makani, JulieView profile | Tropical Medicine & Global Health |
| Developing high throughput methods for production of human membrane proteins for structural studies and drug design. (reference number 226) View project | Carpenter, LizView profile | Protein Science & Structural Biology |
| Development and application of analytical methods for human genetic data (reference number 100) View project | Donnelly, PeterView profile | Bioinformatics & Statistics |
| Development of bioinformatics tools for improving the experimental production of protein samples (reference number 117) View project | Esnouf, RobertView profile | Protein Science & Structural Biology |
| Development of high throughput field adapted antimalarial drug assays primarily for infants and young children (reference number 244) View project | Lindegardh, NiklasView profile | Tropical Medicine & Global Health |
| Development of novel approaches to model large series of heterogenous pharmacological data (reference number 245) View project | Lindegardh, NiklasView profile | Tropical Medicine & Global Health |
| Discovery and characterization of novel ERAD components (reference number 213) View project | Christianson, JohnView profile | Molecular & Cell Biology |
| Does HIF hydroxylase inhibition produce robust biological benefits in rat hind-limb ischaemia? (reference number 92) View project | Pugh, ChrisView profile | Molecular & Cell Biology |
| ENU mutants affecting the immune response to antigens (reference number 101) View project | Cornall, RichardView profile | Immunology |
| Epidemiological research on vegetarians: nutritional status and long-term health (reference number 225) View project | Key, TimView profile | Clinical Trials & Epidemiology |
| Epigenetic inheritance in cancer stem cells and their normal counterparts (reference number 216) View project | Goding, ColinView profile | Cancer |
| Evaluation into the immunological mechanisms induced by mycobacteria and the potential effect this may have upon immunity induced by tuberculosis vaccines. (reference number 247) View project | McShane, HelenView profile | Immunology |
| Evolutionary Epidemiology of Influenza (reference number 121) View project | Farrar, JeremyView profile | Tropical Medicine & Global Health |
| Examining the immune pathways involved in lung fibrosis in idiopathic pulmonary fibrosis and fibrotic sarcoidosis (reference number 234) View project | Ho, Ling-PeiView profile | Immunology |
| Extensive multiplex and deep sequencing methods for pathogen identification in Pneumonia & Pleural Infection (reference number 232) View project | Davies, RobertView profile | Immunology |
| FOXP2 as a molecular window into speech and language disorders (reference number 82) View project | Fisher, SimonView profile | Behavioural & Neuroscience |
| Functional characterization of the KIAA0319 encoded protein and its role in neuronal migration and developmental dyslexia (reference number 23) View project | Monaco, AnthonyView profile | Behavioural & Neuroscience |
| Functional genomics of innate immunity (reference number 187) View project | Knight, JulianView profile | Genetics & Genomics |
| Functional investigation of susceptibility genes for specific language impairment (SLI) (reference number 24) View project | Monaco, AnthonyView profile | Behavioural & Neuroscience |
| Gene Therapy for Endocrine Tumours (reference number 21) View project | Thakker, RajeshView profile | Endocrinology & Metabolic Medicine |
| Genetics of endometrial cancer (reference number 188) View project | Tomlinson, IanView profile | Genetics & Genomics |
| HIV Adaptation to New Human Hosts (reference number 32) View project | Phillips, RodneyView profile | Immunology |
| High throughput screen to identify ligands for the activating NK receptor KIR3DS1, in HIV-1 infection (reference number 249) View project | Gillespie, GeraldineView profile | Immunology |
| How and why do immune responses control iron transport? (reference number 194) View project | Drakesmith, Alexander HalView profile | Immunology |
| How does the immune response in acute HIV infection determine clinical outcome? (reference number 99) View project | Frater, JohnView profile | Immunology |
| Hypoxia Signalling across the Mammalian Proteome (reference number 116) View project | Ratcliffe, PeterView profile | Molecular & Cell Biology |
| Identifying genetic factors determining foetal haemoglobin levels in Sickle Cell Disease (reference number 220) View project | Makani, JulieView profile | Tropical Medicine & Global Health |
| Identifying the cause of acidosis in malaria (reference number 128) View project | White, NicholasView profile | Tropical Medicine & Global Health |
| Immune selection of persistent viruses within populations; 2. Acute HIV infection (reference number 17) View project | Phillips, RodneyView profile | Immunology |
| Improving the treatment of malaria (reference number 129) View project | White, NicholasView profile | Tropical Medicine & Global Health |
| Improving vaccines by altering the migration of lymphocytes (reference number 19) View project | Beverley, PeterView profile | Immunology |
| Influenza Vaccine Development (reference number 240) View project | Gilbert, SarahView profile | Immunology |
| Innate Immunity in the Honey Bee - The case of Colony Collapse Disorder (reference number 219) View project | Harkiolaki, MariaView profile | Protein Science & Structural Biology |
| Interactions in groups of flies (reference number 223) View project | Claridge-Chang, AdamView profile | Behavioural & Neuroscience |
| Internet methods for dietary assessment in the UK Biobank study (reference number 152) View project | Clarke, RobertView profile | Clinical Trials & Epidemiology |
| Investigation of candidate factors that facilitate MHC class I-mediated containment of HIV-1. (reference number 237) View project | Gillespie, GeraldineView profile | Immunology |
| Investigation of the IL-23/Th17 axis in inflammatory bowel disease (reference number 215) View project | Powrie, FionaView profile | Immunology |
| Investigation of the function of NOD2 in Crohn’s disease (reference number 57) View project | Simmons, AlisonView profile | Tropical Medicine & Global Health |
| Investigation of the role of T cells in the pathogenesis of atopic eczema (reference number 46) View project | Ogg, GrahamView profile | Immunology |
| Involvement of Common Fragile Sites in Autism Susceptibility (reference number 203) View project | Volpi, EmanuelaView profile | Genetics & Genomics |
| Isolation and identification of novel ERAD substrates (reference number 214) View project | Christianson, JohnView profile | Molecular & Cell Biology |
| Lactose, lactase gene-variants, dairy intake and cancer: Exploiting Mendelian randomisation to explore the relationships between cancer and nutrition (reference number 235) View project | Travis, RuthView profile | Clinical Trials & Epidemiology |
| Low frequency DNA variants and their contribution to individual predisposition to common diseases. (reference number 86) View project | McCarthy, MarkView profile | Endocrinology & Metabolic Medicine |
| Mechanistic analysis of therapeutic receptor superagonism at the single-molecule level (reference number 191) View project | Davis, SimonView profile | Immunology |
| Method for Real-time DNA Sequencing (reference number 104) View project | Mir, KalimView profile | Genetics & Genomics |
| Methods for Sequencing Genomes (reference number 102) View project | Mir, KalimView profile | Genetics & Genomics |
| Mitf and the DNA damage response (reference number 66) View project | Goding, ColinView profile | Cancer |
| Molecular Biology of Iron Metabolism (reference number 94) View project | Townsend, AlainView profile | Molecular & Cell Biology |
| Molecular Machines: Structural Studies of Chromatin Remodeling Complexes (reference number 119) View project | Mancini, ErikaView profile | Protein Science & Structural Biology |
| Molecular Mechanisms of Parathyroid Gland Development (reference number 22) View project | Thakker, RajeshView profile | Endocrinology & Metabolic Medicine |
| Molecular mechanisms of the Hedgehog signalling pathway (reference number 118) View project | Siebold, ChristianView profile | Molecular & Cell Biology |
| Molecular-dynamic correlates of oxidant haemolysis in glucose-6-phosphate dehydrogenase (G6PD) deficiency (reference number 126) View project | White, NicholasView profile | Tropical Medicine & Global Health |
| Monocyte function in Ankylosing Spondylitis (reference number 35) View project | Bowness, PaulView profile | Immunology |
| Nicotinic acid receptor signaling in adipocytes and regulation of HDL cholesterol (reference number 31) View project | Karpe, FredrikView profile | Endocrinology & Metabolic Medicine |
| Novel Methodologies for the Generation of Genetically Modified Models (reference number 130) View project | Davies, BenView profile | Genetics & Genomics |
| Nutrient biomarkers and the risk of cardiovascular disease in EPIC-Oxford. (reference number 27) View project | Spencer, ElizabethView profile | Clinical Trials & Epidemiology |
| Olfactory behaviour in Drosophila (reference number 106) View project | Claridge-Chang, AdamView profile | Behavioural & Neuroscience |
| Phosphorylation of the deubiquitinating enzyme otubain1 by a kinase oncogene suggests role in cell migration/cancer (reference number 207) View project | Kessler, BenediktView profile | Immunology |
| Population Genetics of Influenza Surveillance in Vietnam (reference number 120) View project | Farrar, JeremyView profile | Tropical Medicine & Global Health |
| Poxviral immune modulation and evasion: improving vaccine vector immunogenicity. (reference number 111) View project | Gilbert, SarahView profile | Immunology |
| Proteases with Deubiquitylating Activity in Neurons (reference number 208) View project | Kessler, BenediktView profile | Immunology |
| Proteomics discovery and characterization of novel deubiquitylating enzymes (reference number 85) View project | Kessler, BenediktView profile | Immunology |
| Regulation of ERAD genes in cancer (reference number 212) View project | Christianson, JohnView profile | Molecular & Cell Biology |
| Regulation of innate immune response in the lungs during lethal influenza A virus infection (reference number 233) View project | Ho, Ling-PeiView profile | Immunology |
| Regulation of ligands identifying diseased cells for immune destruction -role of a novel transcription factor. (reference number 28) View project | O'Callaghan, ChrisView profile | Immunology |
| Research Methodology in Global Health Clinical Trials. (reference number 204) View project | Lang, TrudieView profile | Tropical Medicine & Global Health |
| Statistical methods for the analysis of genetic association studies (reference number 147) View project | Donnelly, PeterView profile | Genetics & Genomics |
| Structural Characterization and Chemical Biology of Jumonji-Domain Containing Lysine Demethylases (reference number 77) View project | Heightman, TomView profile | Protein Science & Structural Biology |
| Structural analysis of membrane bound virus entry (reference number 238) View project | Grunewald, KayView profile | Protein Science & Structural Biology |
| Structural aspects of caveolae assembly (reference number 239) View project | Grunewald, KayView profile | Protein Science & Structural Biology |
| Structural biology of cell surface receptors. (reference number 114) View project | Jones, E. YvonneView profile | Protein Science & Structural Biology |
| Structural studies of pore formation in infection and immunity. (reference number 88) View project | Gilbert, RobertView profile | Protein Science & Structural Biology |
| Structural studies of translation initiation and elongation (reference number 89) View project | Gilbert, RobertView profile | Protein Science & Structural Biology |
| Structure and function of the platelet activating receptor CLEC-2 and its ligands. (reference number 56) View project | O'Callaghan, ChrisView profile | Immunology |
| Structure-based strategies for better picornavirus vaccines (reference number 241) View project | Stuart, DavidView profile | Protein Science & Structural Biology |
| Structure-function studies of tumour suppressor protein INI1, a core subunit of a mammalian chromatin remodelling complex (reference number 109) View project | Mancini, ErikaView profile | Protein Science & Structural Biology |
| Systematic analysis of NF-kB/IRF/ - DNA affinities (reference number 107) View project | Ragoussis, IoannisView profile | Molecular & Cell Biology |
| T cell control of varicella zoster virus (reference number 45) View project | Ogg, GrahamView profile | Immunology |
| Targeting Vaccine-Elicited HIV-1-Specific T Cells to the Gut (reference number 243) View project | Hanke, TomasView profile | Immunology |
| Targeting and increasing HIV-specific CTL responses using antigen processing optimized vaccine contructs (reference number 246) View project | Iversen, AstridView profile | Immunology |
| The 1000 Genomes Project (reference number 148) View project | Donnelly, PeterView profile | Genetics & Genomics |
| The Identification and Analysis of Genetic Variants in the p53 Tumor Suppressor Pathway that Affect Cancer in Humans (reference number 70) View project | Bond, GarethView profile | Cancer |
| The Identification and Analysis of Genetic Variants that Affect Cancer in Humans: A Quantitative Approach (reference number 155) View project | Bond, GarethView profile | Genetics & Genomics |
| The Identification and Analysis of Genetic Variants that Mediate the Responses to Cancer Therapies. (reference number 71) View project | Bond, GarethView profile | Cancer |
| The Immunopathology of Acute HIV Infection (reference number 176) View project | Frater, JohnView profile | Immunology |
| The Molecular Roots of Multiple Sclerosis (reference number 113) View project | Harkiolaki, MariaView profile | Protein Science & Structural Biology |
| The ecology and population genetics of Orientia tsutsugamushi in trombiculid mites in Thailand and Lao PDR (reference number 127) View project | Day, NickView profile | Tropical Medicine & Global Health |
| The epidemiology of prostate cancer (reference number 231) View project | Allen, NaomiView profile | Clinical Trials & Epidemiology |
| The function of dendritic cells in HIV-2 infection (reference number 39) View project | Rowland-Jones, SarahView profile | Tropical Medicine & Global Health |
| The role of iASPP in the fate decisions of epithelial stem cells (reference number 59) View project | Lu, XinView profile | Cancer |
| The role of iron metabolism in HIV replication and AIDS pathogenesis (reference number 73) View project | Drakesmith, Alexander HalView profile | Endocrinology & Metabolic Medicine |
| The role of the ASPP proteins in neuronal stem cells and the development of neurodegenerative disease (reference number 58) View project | Lu, XinView profile | Cancer |
| The structural biology of GABAB receptors (reference number 112) View project | Aricescu, AlexandruView profile | Protein Science & Structural Biology |
| Theoretical Population Genetics, Theoretical Population Dynamics, and Disease (reference number 122) View project | Horby, PeterView profile | Tropical Medicine & Global Health |
| Therapeutic immunomodulation in HIV-1 infection (reference number 248) View project | Dorrell, LucyView profile | Immunology |
| Transcriptional pathways controlling vessel development in disease states (reference number 211) View project | De Val, SarahView profile | Molecular & Cell Biology |
| Transposon capture of resistance plasmids from unculturable bacteria (reference number 149) View project | Dunstan, SarahView profile | Tropical Medicine & Global Health |
| What makes an effective T-cell response against HIV-1 infection? studies in a unique Chinese cohort (reference number 40) View project | Rowland-Jones, SarahView profile | Tropical Medicine & Global Health |
| Whole genome association study of depression (reference number 123) View project | Flint, JonathanView profile | Behavioural & Neuroscience |
| Worldwide Antimalarial Resistance Network (WWARN) project (reference number 154) View project | Guerin, PhilippeView profile | Tropical Medicine & Global Health |
| “Kiss-and-run” insulin secretion as a cause of type-2 diabetes? (reference number 30) View project | Rorsman, PatrikView profile | Endocrinology & Metabolic Medicine |