Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

<jats:title>Key Points</jats:title> <jats:p>The N-terminus of ERFE binds BMP6 with nanomolar affinity and is sufficient to inhibit BMP signaling and suppress hepcidin in vivo Anti-N-terminal ERFE antibodies prevent Epo-induced hepcidin suppression and decrease iron accumulation and anemia in thalassemic mice</jats:p>

Original publication

DOI

10.1182/blood.2019003140

Type

Journal article

Journal

Blood

Publisher

American Society of Hematology

Publication Date

03/01/2020