Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Synchronous field-potential bursts were induced in hippocampal slices with picrotoxin. Differential recording between intracellular and adjacent extracellular electrodes during paroxysmal depolarization shifts revealed rapid transmembrane depolarizations (TMDs), which were spike prepotentials generated by electrical field effects. These experiments demonstrate that endogenous electrical fields contribute to spike synchronization in the presence of convulsant drugs when excitatory chemical synapses are functional.

Original publication

DOI

10.1016/0006-8993(84)90271-3

Type

Journal article

Journal

Brain research

Publication Date

12/1984

Volume

323

Pages

114 - 118

Keywords

Hippocampus, Animals, Rats, Epilepsy, Picrotoxin, Cortical Synchronization, Action Potentials, Electromagnetic Fields, In Vitro Techniques