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Using an ELISA technique, concentrations of γ-interferon and interleukin-2 were assayed in the supernatants of colonic intraepithelial lymphocytes cultured with or without phytohaemagglutinin (PHA). IntraepitheHal lymphocytes produced low concentrations of γ-interferon and interleukin-2 when stimulated with PHA, but significantly more than when unstimulated (p<0.05). There was no difference in production of these cytokines by IEL from control or inflammatory bowel disease.

Original publication

DOI

10.1155/s0962935194000311

Type

Journal article

Journal

Mediators of Inflammation

Publisher

Hindawi Limited

Publication Date

1994

Volume

3

Pages

219 - 222