Cassandra Adams
D.Phil.
Translational Scientist and Senior Programme Manager
Cassandra Adams is a translational scientist in the Centre for Medicines Discovery. She received her D.Phil. in Clinical Laboratory Sciences at the University of Oxford in 2010 under the supervision of Prof. Nick La Thangue. She then undertook post-doctoral research on radiation-induced tumorigenesis in the laboratory of Prof. Allan Balmain at the University of California, San Francisco (UCSF). During which time she was awarded a full fellowship from the Leukemia and Lymphoma Society. Subsequently she became a senior staff scientist in Genome Analysis Core Facility, UCSF where she launched and managed the new Single Cell Analysis Center.
Cassandra joined the BRC team in 2018 as a translational scientist and is currently working on a range of projects accelerating novel drug targets downstream in a variety of therapeutic areas with a primary focus on oncology.
Recent publications
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Mutational signatures in tumours induced by high and low energy radiation in Trp53 deficient mice
Journal article
Rose Li Y. et al, (2020), Nature Communications, 11
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Quantifying Gene Expression Directly from FACS Using Hydrolysis (TaqMan) Probes on Flash-frozen Cells
Journal article
Copren K. et al, (2018), BIO-PROTOCOL, 8
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The Trp53
delta proline (Trp53ΔP
) mouse exhibits increased genome instability and susceptibility to radiation-induced, but not spontaneous, tumor development
Journal article
Adams CJ. et al, (2016), Molecular Carcinogenesis, 55, 1387 - 1396
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Systems biology perspectives on the carcinogenic potential of radiation
Journal article
Barcellos-Hoff MH. et al, (2014), Journal of Radiation Research, 55, i145 - i154
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The p53 cofactor Strap exhibits an unexpected TPR motif and oligonucleotide-binding (OB)-fold structure
Journal article
Adams CJ. et al, (2012), Proceedings of the National Academy of Sciences, 109, 3778 - 3783