Colleges
Ian Tomlinson
Professor of Molecular and Population Genetics
- The identification of genes that predispose to colorectal and other cancers
- Functional genetics of colorectal tumorigenesis, with emphasis on the relative importance of selection and genomic instability.
- Cancer genes and metabolism.
- Cancer evolution.
Recent publications
-
JAK/STAT3 represents a therapeutic target for colorectal cancer patients with stromal-rich tumors.
Journal article
Pennel KAF. et al, (2024), Journal of experimental & clinical cancer research : CR, 43
-
Intra-prostatic tumour evolution, steps in metastatic spread and histogenomic associations revealed by integration of multi-region whole-genome sequencing with histopathological features.
Journal article
Rao S. et al, (2024), Genome medicine, 16
-
Combining Asian and European genome-wide association studies of colorectal cancer improves risk prediction across racial and ethnic populations.
Journal article
Thomas M. et al, (2023), Nature communications, 14
-
Accounting for intensity variation in image analysis of large-scale multiplexed clinical trial datasets.
Journal article
Frei AL. et al, (2023), The journal of pathology. Clinical research
-
Functional analysis reveals driver cooperativity and novel mechanisms in endometrial carcinogenesis
Journal article
Brown M. et al, (2023), EMBO Molecular Medicine