They have ensured high data quality and been able to impute the number of testable genetic variants – the letters in our DNA code that vary from person to person - from 800,000 to 96 million, a more than 100-fold increase in useful data. Imputation compares the selected genotyped DNA with analysis of the full human genome, to allow scientists to accurately predict DNA code at non-selected sections.
'Tantalising and exciting’: UK Biobank genetics opens the door to a new era of health research
12 October 2018
A team of Oxford University researchers have worked on behalf of UK Biobank to apply sophisticated new statistical techniques to genetic information from all 500,000 volunteer UK Biobank participants.