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A team of Oxford University researchers have worked on behalf of UK Biobank to apply sophisticated new statistical techniques to genetic information from all 500,000 volunteer UK Biobank participants.

They have ensured high data quality and been able to impute the number of testable genetic variants – the letters in our DNA code that vary from person to person - from 800,000 to 96 million, a more than 100-fold increase in useful data. Imputation compares the selected genotyped DNA with analysis of the full human genome, to allow scientists to accurately predict DNA code at non-selected sections.

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