Scientists from the University of Oxford\u2019s Nuffield Department of Medicine have today published their evaluation of LamPORE, a novel diagnostic platform for detecting SARS-CoV-2 RNA. It combines loop-mediated isothermal amplification with nanopore sequencing. This technology has the potential to analyse thousands of samples per day on a single instrument.
A team of mathematical modellers and epidemiologists at Oxford University\u2019s Nuffield Department of Medicine release the latest model of a population responding to the coronavirus epidemic. The model - OpenABM-Covid19 - provides public health decision-makers with the ability to review the potential progression and outcome of the coronavirus, including fluctuations in infected individuals, hospitalisations, intensive care unit (ICU) admissions and deaths, and assess the impact of test and trace programmes.
The latest research findings from a team of modellers and epidemiologists at Oxford University\u2019s Nuffield Department of Medicine and Google Research suggest digital contact tracing, such as that based on Google and Apple\u2019s Exposure Notification System (ENS), can help to control the epidemic at low levels of app uptake.
Oxford University researchers have found that natural infection with COVID-19 produces a robust T cell response, including inducing T cell \u2018memory\u2019 to potentially fight future infections.
Ludwig Oxford's Dr Tammie Bishop organised a week of work experience for fifteen year 12 students in collaboration with the Magdalen Outreach Team. University Research Lecturer Dr Tammie Bishop works in the laboratory led by 2019 Nobel Prize-winning Sir Peter Ratcliffe (Target Discovery Institute & Ludwig Institute for Cancer Research) which conducts research into hypoxia, as well as currently being involved in research into the role of hypoxia in SARS-CoV-2.
The Department of Health & Social Care announced the latest version of the contact tracing app will be tested on the Isle of Wight and with NHS volunteers from this week, and in the London Borough of Newham from next week. The app will enable you to report your symptoms and book a test directly through the app. If you test positive for COVID-19, your close proximity contacts from the last 2 weeks will be notified and advised to isolate to prevent onward spread of the virus.
The Royal Society has today announced that it is awarding its Gabor Medal to David Stuart, who is Professor of Structural Biology in the Nuffield Department of Medicine and the Life Sciences Director of the Diamond Light Source, the National Synchrotron at Harwell. Professor Stuart is currently leading a large number of projects relating to the University\u2019s response to COVID19, which include studying the structure of SARS-Cov-2 and a series of anti-viral drug discovery programmes. He is also leading the Oxford research team providing antibody immunity data on the UK population for the Office of National Statistics.
A team of scientists at NDM\u2019s Jenner Institute and The Oxford Vaccine Group has taken the next step towards the discovery of a safe, effective and accessible vaccine against coronavirus. The results of the Phase I/II trial published recently in the scientific journal, The Lancet, indicate no early safety concerns and induces strong immune responses in both parts of the immune system.
team of epidemiologists, mathematical modellers and economists at NDM's Big Data Institute has released an independent analysis of the trends in the number of coronavirus infections (incidence) on the Isle of Wight, UK before and during the first phase of the test and trace programme (TT), including the first version of the NHS contact tracing app. Results of the study, which has not yet been subject to formal peer review, can be explored on EpiNow interactive tool.
Many congratulations to the members of the NDM who have been awarded the title of Associate Professor or University Research Lecturer in this year\u2019s Recognition Of Distinction exercise! The full list of recipients can be found here:
A generous gift of \u00a33.5 million from Lakshmi Mittal and his family has secured the future of a critical professorship in vaccinology at the University. The post, which is currently held by NDM's Professor Adrian Hill, will be known as the Lakshmi Mittal and Family Professorship of Vaccinology in recognition of this support.
Yang Shi has been appointed a Member of the Ludwig Institute for Cancer Research to continue his research into chromatin, RNA modifications and cancer. He joins NDM's Ludwig Institute from Harvard University, and is a world leader in the field of epigenetics, which explores how chemical modifications to chromatin\u2014the combination of DNA and histone proteins-control the organisation and expression of the human genome.
The Duke of Cambridge visits the University of Oxford\u2019s Oxford Vaccine Centre, to learn more about their work to establish a viable vaccine against COVID-19. The Duke paid a visit to the Oxford Vaccine Centre facility at the Churchill Hospital in Oxford where the vaccine has been developed and trials are now underway. During his visit, The Duke was briefed about the Group\u2019s work by NDM's Professor Sarah Gilbert, Professor of Vaccinology at the Jenner Institute, who developed the vaccine and Professor Andrew Pollard, Professor of Paediatric Infection and Immunity, who is leading the clinical trial team.
Originally screened live on Friday 22nd May 2020, here is another chance to view the Vice-Chancellor, Professor Louise Richardson, being joined by Professor Richard Cornall, Head of the Nuffield Department of Medicine, to talk about the University's research into the COVID-19 virus.
NDM's Dr Anita Milicic from the Jenner Institute, Old Road Campus Research Buillding and Dr Calliope Dendrou from the Wellcome Centre for Human Genetics, are part of a group with Professor Mark Coles from the Kennedy Institute who have received a share of $14 million in funding from the Chan Zuckerberg Initiative as one of 29 projects that will explore emerging ideas regarding the role of inflammation in disease.
The University of Oxford has today announced an agreement with the UK-based global biopharmaceutical company AstraZeneca for the further development, large-scale manufacture and potential distribution of the COVID-19 vaccine candidate currently being trialled by the University.
The world\u2019s largest randomised clinical trial of potential coronavirus treatments is well underway in the UK as part of the race to find a treatment.
A team of medical researchers and bioethicists at Oxford University has published results today in Science that further our understanding of coronavirus transmission.
The three projects include work on an effective vaccine, enabling pre-clinical and clinical vaccine trials, as well as supporting researchers to develop manufacturing processes to produce a vaccine at a million-dose scale.
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