Professor Gyrd-Hansens group at Ludwig Cancer Research is seeking an exceptional and motivated postdoctoral scientist with experience in experimental murine models to undertake a project that focusses on the role of the ubiquitin machinery in immune regulation in vivo.
Our research is focused on understanding how the ubiquitin system controls innate immune processes that protect against infectious agents but, when inappropriately activated, also contribute to chronic inflammation and cancer. Our long-term goal is to identify molecular processes that can be targeted pharmacologically to treat cancer and other inflammation-driven pathologies.
More information about the research led by Professor Gyrd-Hansen can be found here: www.ludwig.ox.ac.uk/mads-gyrd-hansen-group-page
You should have previous laboratory experience relevant to the project. Good attention to detail and an ability to work both independently and as part of a team is essential. You will use of a wide range of experimental methodologies, including phenotypic analysis, isolation and analysis of primary cells, and establishment of murine cell lines. In addition, your work will involve biochemical, molecular and cell biology techniques, including but not limited to multiplex flow cytometry, CYTOF, fluorescence imaging, next-generation sequencing, biochemical analysis of ubiquitin signalling pathways. Previous relevant experience using in vivo models and animal breeding and colony management will be required. You should have a good publication record. A valid UK home office personal license to undertake animal work and previous experience in ubiquitin signalling is desirable.
Applications for this vacancy are to be made online, and as part of the application you will be required to upload a CV and supporting statement.
Only applications received before 12.00 noon on Monday 3 June 2019 will be considered.
Contact: HR Officer (01865 617971)