Clinical Researcher

Experimental Medicine, Nuffield Department of Clinical Medicine, Translational Gastroenterology Unit, John Radcliffe Hospital, Headington, Oxford

Applications to be received by 12pm on Friday 6th of March 2020

Grade E64: £33,221- £53,244 p.a.

We are seeking a Clinical Researcher to join Professor Jack Satsangi’s group at the Translational Gastroenterology Unit situated in the John Radcliffe Hospital. You will work with non-clinical and clinical scientists in Oxford to develop and validate biomarkers in liquid and intestinal biopsies from patients with inflammatory bowel disease. You will be a member of a research group with responsibility for carrying out translational research in inflammatory bowel disease.


Building on previous work by the research group, and the IBD-BIOM and IBD-CHARACTER Consortia, you will develop assays for epigenetic, proteomic, and glycomic biomarkers that predict the clinical course in inflammatory bowel disease, and also predict primary and secondary response/non-response to biological agents, including anti-TNF therapy and apply these in samples from patient cohorts. The postholder interacts with clinical and non-clinical scientists, and members of the biobanking teams and provides guidance to less experienced members of the research group, including postdocs, research assistants, technicians, and PhD and project students.


The post will suit either a clinician, and provide a basis for developing research skills before applying for a research training fellowship; or an experienced trainee with a higher degree nearing/having reached accreditation who wishes to develop their knowledge in translational medicine, and apply for an intermediate fellowship, or academic positions. Opportunities are available for developing projects either in biomarker discovery, or in basic science, to understand the biological relevance of markers identified with a view to target discovery, with a series of collaborations in place.


You will interact with clinicians and scientists across the campus in Oxford and with other national and international collaborators, notably in this project with colleagues in Amsterdam. Strong support will be given for developing further scientific work. You will hold a relevant medical degree: Bachelor of Medicine and Bachelor of Surgery or equivalent. You will also have GMC registration and an active interest in translational research, with respect to optimizing the use of new agents in chronic disease, by personalisation of care.


This post is full-time and fixed-term until 31 December 2021.


Applications for this vacancy are to be made online. You will be required to upload a supporting statement and CV as part of your online application. Please quote reference 145179 on all correspondence.


Only applications received before 12.00 midday on 6 March 2020 will be considered.

Contact: HR Officer