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Antonio Berlanga-Taylor

Antonio Berlanga-Taylor

Antonio Berlanga-Taylor

MRC Intermediate Research Fellow in Computational Biology and Epidemiology, MRC-PHE Centre for Environment and Health, Department of Epidemiology & Biostatistics, School of Public Health, Faculty of Medicine, Imperial College London

After graduating in medicine (UNAM, Mexico), I obtained an MSc in Immunology (NDM, Oxon), a DPhil in Genomic Medicine (NDM, Oxon), held an MRC CGAT Fellowship in Computational Genomics at the University of Oxford and currently work as an MRC Intermediate Research Fellow in Computational Biology and Epidemiology, MRC-PHE Centre for Environment and Health, at Imperial College London. My research interests lie at the intersection of inflammation and genomics and aim to understand the interactions between our genes and the environment. I use both wet lab and computational methods. I previously focussed on vitamin D-gene interactions in immunity and I am now exploring inflammatory responses using an integrated approach based on genomics and metabolomics in large prospective studies of chronic disease. My research leverages the strength of cohort and clinical trial designs with computational and mechanistic studies in order to understand causal roles of genetic and environmental factors in immune and inflammatory disorders. I have previously held various clinical and public health roles in Colombia and Mexico and was a Scholar for Chevening, CONACyT (Mexico), the Ministry of Education (Mexico) and the Multiple Sclerosis Society of the UK.

I am currently collaborating with Prof Constantino III Roberto López-Macías from the Mexican Institute for Social Security (IMSS) and with Dr Miguel Antonio García Knight. An important aim of my collaborations with Mexican researchers and clinicians is to increase genomics capacity for both research and clinical applications.

Together with Prof López-Macías, Prof Arturo Reyes-Sandoval and Dr Miguel Antonio García-Knight, I obtained funding and organised the 2015 MX-UK Workshop on Genome research and human health: current applications and translational potential in inflammation and infectious diseases. In April 2016 I participated as part of the Scientific Committee of the XXII Mexican National Congress of Immunology - "New Trends in Immunology" that took place in Zacatecas, Mexico, together with Prof López-Macías, Dr José Antonio Enciso-Moreno (UIBMZ-IMSS) and Dr Julio Enrique Castañeda Delgado (CONACyT, UIBMZ-IMSS). At this event I organised a symposium, delivered a lecture and workshop on computational biology.

I have continued ties with Oxford and NDM working with Professor Julian C. Knight, acting as co-supervisor of NDM’s DPhil candidate Alicia Lledo-Lara and with CGAT.

Selected Publications

Disanto G, Kjetil Sandve G, Ricigliano VA, et al., 2014, DNase hypersensitive sites and association with multiple sclerosis., Hum Mol Genet, Vol:23, Pages:942-948.

Elangovan RI, Disanto G, Berlanga-Taylor AJ, et al., 2014, Regulatory genomic regions active in immune cell types explain a large proportion of the genetic risk of multiple sclerosis., J Hum Genet, Vol:59, Pages:211-215.

Berlanga-Taylor AJ, Knight JC, 2014, An integrated approach to defining genetic and environmental determinants for major clinical outcomes involving vitamin D., Mol Diagn Ther, Vol:18, Pages:261-272.