A team of researchers at NDM\u2019s Oxford University Clinical Research Unit (OUCRU) has pioneered a novel, microbiological assay-independent diagnostic model for adult Tuberculous Meningitis, leveraging Bayesian latent class analysis to improve the accuracy of diagnoses. This innovative approach, promises to enhance the detection and treatment of one of the most severe forms of tuberculosis (TB).
The phase III trial data results of the R21/Matrix-M vaccine, developed by the Jenner Institute and the Serum Institute of India have confirmed high efficacy and supported regulatory approvals and licensure in several African countries.
The largest multiparameter immunoprofiling study in cancer to date has suggested an underappreciated role of a subset of immune cells in determining the risk of bowel cancer relapse after surgery.
A new hepatitis B study reveals how viruses adapt to low-oxygen environments, such as those found deep within the liver, opening up possible new therapeutic targets for liver pathogens. NDM researchers have identified hypoxia-inducible factors (HIFs) playing an important role in the regulation of editing of viral RNAs in low oxygen conditions.
The Big Data Institute along with the collaborators have developed a new, easy-to-use technique for hospitals to contribute to developing artificial intelligence (AI) models, without patient data leaving the hospital\u2019s premises.
A recent study by the Mahidol-Oxford Tropical Medicine Research Unit (MORU) at NDM outlined a highly effective method for dengue surveillance. The researchers improved risk detection in real time by combining space-time modelling and anomaly detection. This will help in making dengue prevention more effective not only in Thailand but also in other regions with similar challenges.
A recent study by NDM\u2019s Mahidol Oxford Tropical Medicine Research Unit researchers highlighted that there was no difference in the rate of viral clearance between patients given Favipiravir and patients receiving no study drug.
A recent study led by the Centre for Human Genetics at NDM has revealed that areas of the human genome that are routinely overlooked in clinical tests may be the cause of some rare diseases.
A new study by researchers from the Ethox Centre and NDM has highlighted important ethical considerations in Nipah virus outbreak control, its treatment, and research into vaccines.
A teledermatology initiative by Oxford University Clinical Research Unit (OUCRU) Indonesia, in partnership with the Sumba Foundation and Gadjah Mada University, has made significant strides in transforming rural healthcare in Eastern Indonesia.
In a recent study, NDM\u2019s Mahidol Oxford Tropical Medicine Research Unit (MORU) researchers introduced an anomaly detection system, as an early warning mechanism for potential malaria outbreaks in countries like Thailand.
Researchers from the Mahidol Oxford Tropical Medicine Research Unit at NDM, in a recent study, analysed the uptake of community health workers' services and the effectiveness of this programme in controlling and eliminating malaria.
A recent study by researchers at the Pandemic Sciences Institute shows that the NHS COVID-19 contact tracing app successfully predicted people\u2019s risk of catching the virus following exposure to an infected person.
A new study by Pandemic Sciences Institute, Ethox Centre, Mahidol-Oxford Tropical Medicine Research at the Centre for Tropical Medicine and Global Health and Royal Melbourne Hospital Department of Medicine, sheds light on important ethical considerations in Nipah virus outbreak control, its treatment, and research into vaccines.
A recent study by the PANGEA-HIV consortium, including researchers from the Pandemic Sciences Institute and Big Data Institute at NDM, has generated the largest dataset of HIV genomes in Southern and Eastern Africa to improve the current understanding of the epidemic.
To boost the fight against drug-resistant malaria parasites now emerging in Africa, researchers at the Mahidol Oxford Tropical Medicine Research Unit will study the safety and efficacy of a fixed-dose combination (FDC) containing three antimalarial drugs currently given to patients separately in a triple artemisinin-based combination therapy (TACT) cocktail.
The study by Oxford University Hospitals and NHS Foundation Trust researchers is the first to test the acceptability of transdermal sampling in children. Sixty-three percent of participants preferred this method to a needle, while just seven percent preferred the needle.
A recent study by NDM researchers and collaborators estimates that nearly 1 in 4 people with P. falciparum malaria in Africa are at risk of receiving too low a dose of artemisinin combination therapies (ACTs). This increases the chance of treatment failure and the risk that malarial parasites develop resistance to the drug they were exposed to.
Researchers from the CAMS Oxford Institute and NDM Target Discovery Institute, including Prof Benedikt Kessler and Dr Ad\u00e1n Pinto-Fern\u00e1ndez, have collaborated with the team of Dr Paul Geurink and Dr Aysegul Sapmaz from Leiden University to investigate an important interferon-stimulated gene, ISG15.
A meta-analysis of nearly 30,000 patients by the The Infectious Diseases Data Observatory researchers, suggests that a post-treatment follow-up duration of longer than 6-months may be needed to identify visceral leishmaniasis relapses.
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