The R21/Matrix-M\u2122\u202fmalaria vaccine, developed by the Jenner Institute, and manufactured by the Serum Institute of India which leverages Novavax\u2019s adjuvant technology, has been licensed for use in Burkina Faso by the country\u2019s regulatory agency, Agence Nationale de la Regulation Pharmaceutique.
NDM is pleased to announce that Professor Paul Brennan has been appointed to be the new Director of the Centre for Medicines Discovery (CMD). Dr Emma Mead will take over as interim Chief Scientific Officer of the Alzheimer's Research UK Oxford Drug Discovery Institute (ODDI) until a permanent replacement is identified.
Digital health and artificial intelligence have the potential to transform healthcare, making health care management more efficient and accessible. However, a new paper by OURCU student Ho Quang Chanh et al, detailed why engagement with policymakers, local patients and healthcare workers, and integrating with local systems and practice are crucial to ensure that digital health technologies can thrive in low- and middle-income settings.
The Lasker Foundation today announced the five winners of its 10th annual Lasker Essay Contest. The winning submissions were selected from hundreds of essays penned by biomedical graduate students and health professions trainees from 25 countries. The winning essayists explored unanticipated ethical issues encountered during their training and strategies used to address them.
Researchers from across the Nuffield Department of Medicine have published a new article in Science Immunology investigating the role of HLA-E-restricted SARS-CoV-2-specific T cells.
The multisite Phase I HIV-CORE 006 HIV vaccine clinical trial, run by the Globally Relevant AIDS Vaccine Europe-Africa Trials Partnership (GREAT), has concluded successfully. Preliminary analysis of the immunological trial results demonstrates the induction of high frequencies of broadly specific T cells that recognise functionally conserved regions on HIV-1 and are therefore more protective.
A Ludwig Cancer Research study has discovered that the presence of relatively high numbers of immune cells known as monocytes in tumours is linked to better outcomes in oesophageal cancer patients treated with a combination of chemotherapy and immunotherapy, or immunochemotherapy.
Researchers running the University of Oxford-led Com-COV3 study have reported the results of a study assessing the immune response and side effect profile of \u2018mixed\u2019 two-dose COVID-19 vaccine schedules in adolescents aged 12 to 16 years - administering either a full or a one-third (fractional) dose of the Pfizer-BioNTech COVID-19 vaccine or a full dose of the Novavax vaccine at least eight weeks after a first full dose of the Pfizer-BioNTech vaccine.
A DPhil Symposium hosted at the the Jenner Institute last month brought together over 80 DPhil Students, Research Assistants, Technicians and Apprentices across the Nuffield Department of Medicine to network and share their research and career aspirations.
Updated data from the ongoing OCTAVE trial, a collaboration between the Universities of Glasgow, Birmingham and Oxford, show for the first time that most clinically at-risk patients with a range of immunocompromised or immunosuppressed conditions in the UK were protected from severe COVID by the vaccination programme.
The Nuffield Department of Medicine\u2019s Wellcome Centre for Human Genetics (WHG) has received a Silver Engage Watermark from the National Co-ordinating Centre for Public Engagement (NCCPE) for its public engagement efforts.
A delegation from the Ministry of Education (MoE) of the People's Republic of China visited the University of Oxford and was hosted at the Nuffield Department of Medicine (NDM) by Professor Tao Dong, Ita Askonas Professor of Translational Immunology and Director of the Chinese Academy of Medical Sciences Oxford Institute (COI).
In a new study, researchers from IBM and NDM\u2019s Division of Structural Biology and Wellcome Centre for Human Genetics show that new antivirals can be designed with the help of artificial intelligence (AI), developed and potentially validated in months.
NDM\u2019s Infectious Diseases Data Observatory and its global collaborators have developed new case report forms providing researchers with a standardised means of recording any data on visceral leishmaniasis, allowing them to compare studies and relate data to the efficacy of visceral leishmaniasis treatments from different groups of researchers.
Researchers from NDM\u2019s Mahidol Oxford Tropical Medicine Research Unit, the Target Discovery Institute and Centre for Medicines Discovery, the University of Oxford\u2019s Department of Biochemistry, and other collaborating organisations have found a nine-protein diagnostic signature in human cerebrospinal fluid that could discriminate between Japanese encephalitis and other brain infections.
While 17 countries have now achieved trachoma elimination status, there is still work to be done, with trachoma responsible for the blindness or visual impairment of about 1.9 million people worldwide. Collaborators are being invited to join a new research project aimed at assessing the drivers for persistent and recrudescent trachoma.
The annual conference of the Chinese Academy of Medical Sciences Oxford Institute took place in Chengdu, in the Sichuan province of China between 1-3 June 2023.
Professor Sir John Irving Bell, Regius Professor of Medicine at the University of Oxford and former Head of Department of the Nuffield Department of Medicine, has been appointed a Companion of Honour in the King\u2019s Birthday Honours list. He was knighted in 2015 for services to medicine, medical research and the life science industry.
Researchers at the Worldwide Antimalarial Resistance Network (WWARN), hosted by NDM\u2019s Centre for Tropical Medicine and Global Health, have provided unique insights into the epidemiology of malaria in pregnancy. The study explored the relationship between infection and fever and found that submicroscopic malaria was associated with fever in Africa but not in Asia and the Americas.
In order to support the Nuffield Department of Medicine in seeking out new opportunities for innovation and delivering impact across its 24 units, Prof Richard Cornall, the Head of Department, has appointed Prof Bountra in a new role within NDM Strategic.
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