Dan Barouch : Novel HIV vaccine strategies
Professor Dan Barouch tells us about his time in Oxford, as a DPhil student in Professor Andrew McMichael's lab. He also comments on how we do as a field trying to develop HIV vaccines - overall not great since we don't have a vaccine yet, and we have tested only 3 conceps over the last 30 years.
Professor Barouch has demonstrated that cellular immune responses can partially control viral replication. This means that HIV-1 vaccines that generate potent cellular immune responses may provide important benefits even if they fail to afford sterilizing immunity. Professor Barouch has developed chimeric adenovirus vectors, and has advanced these vectors into preclinical studies and phase 1 clinical trials.