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Healthcare workers (n = 803) with mild symptoms were tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (n = 90 positive) and asked to complete a symptom questionnaire. Anosmia, muscle ache, ocular pain, general malaise, headache, extreme tiredness and fever were associated with positivity. A predictive model based on these symptoms showed moderate discriminative value (sensitivity: 91.2%; specificity: 55.6%). While our models would not justify presumptive SARS-CoV-2 diagnosis without molecular confirmation, it can contribute to targeted screening strategies.

Original publication

DOI

10.2807/1560-7917.es.2020.25.16.2000508

Type

Journal article

Journal

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

Publication Date

04/2020

Volume

25

Addresses

Department of Medical Microbiology, Radboud Centre for Infectious Diseases, Radboud university medical centre, Nijmegen, The Netherlands.

Keywords

Humans, Pneumonia, Viral, Coronavirus Infections, Pharyngitis, Cough, Headache, Fever, Fatigue, Patient Isolation, Cohort Studies, Predictive Value of Tests, Health Policy, Adult, Aged, Middle Aged, Health Personnel, Personnel, Hospital, Netherlands, Young Adult, Eye Pain, Pandemics, Myalgia, Betacoronavirus, COVID-19, SARS-CoV-2