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Antibody response against nucleocapsid and spike proteins of SARS-CoV-2 in 11 persons with mild or asymptomatic infection rapidly increased after infection. At weeks 18-30 after diagnosis, all remained seropositive but spike protein-targeting antibody titers declined. These data may be useful for vaccine development.

Original publication

DOI

10.3201/eid2702.204226

Type

Journal article

Journal

Emerging infectious diseases

Publication Date

02/2021

Volume

27

Pages

663 - 666

Keywords

Humans, Nucleocapsid Proteins, Antibodies, Viral, Longitudinal Studies, Time Factors, Adolescent, Adult, Middle Aged, Child, Vietnam, Female, Male, Young Adult, Immunity, Humoral, Asymptomatic Infections, Spike Glycoprotein, Coronavirus, COVID-19, SARS-CoV-2