Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Using data from the UK Register of HIV Sero-converters, we compared the rate of CD4 cell decline in antiretroviral-naive individuals with and without evidence of transmitted drug resistance (TDR). Although there was a suggestion that CD4 cell decline in the first year after seroconversion was faster in those with TDR,there was no evidence of a difference in the rate of decline thereafter. The virological and host determinants of this possible phenomenon are worth further exploration.

Type

Journal article

Journal

AIDS

Publication Date

02/07/2004

Volume

18

Pages

1471 - 1473

Keywords

Adult, CD4 Lymphocyte Count, CD4-Positive T-Lymphocytes, Cohort Studies, Drug Resistance, Viral, Female, HIV Infections, HIV Seropositivity, Humans, Lymphopenia, Male