5-Carboxylcytosine is resistant towards phosphodiesterase I digestion: implications for epigenetic modification quantification by mass spectrometry

Yuan F., Bi Y., Zhang J-Y., Zhou Y-L., Zhang X-X., Song C-X.

5-Carboxylcytosine is found to be resistant to snake venom phosphodiesterase I (PDE1), a 3′ to 5′ exonuclease commonly used in several DNA hydrolysis protocols.

DOI

10.1039/c9ra04375f

Type

Journal article

Publisher

Royal Society of Chemistry (RSC)

Publication Date

2019-01-01T00:00:00+00:00

Volume

9

Pages

29010 - 29014

Total pages

4

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