Kleywegt GJ., Adams PD., Butcher SJ., Lawson CL., Rohou A., Rosenthal PB., Subramaniam S., Topf M., Abbott S., Baldwin PR., Berrisford JM., Bricogne G., Choudhary P., Croll TI., Danev R., Ganesan SJ., Grant T., Gutmanas A., Henderson R., Heymann JB., Huiskonen JT., Istrate A., Kato T., Lander GC., Lok S-M., Ludtke SJ., Murshudov GN., Pye R., Pintilie GD., Richardson JS., Sachse C., Salih O., Scheres SHW., Schroeder GF., Sorzano COS., Stagg SM., Wang Z., Warshamanage R., Westbrook JD., Winn MD., Young JY., Burley SK., Hoch JC., Kurisu G., Morris K., Patwardhan A., Velankar S.

In January 2020, a workshop was held at EMBL-EBI (Hinxton, UK) to discuss data requirements for the deposition and validation of cryoEM structures, with a focus on single-particle analysis. The meeting was attended by 47 experts in data processing, model building and refinement, validation, and archiving of such structures. This report describes the workshop's motivation and history, the topics discussed, and the resulting consensus recommendations. Some challenges for future methods-development efforts in this area are also highlighted, as is the implementation to date of some of the recommendations.

Community recommendations on cryoEM data archiving and validation

DOI

Type

Publisher

Publication Date

Volume

Pages

Total pages