Covalent Fragment Screening and Optimization Identifies the Chloroacetohydrazide Scaffold as Inhibitors for Ubiquitin C-terminal Hydrolase L1

Imhoff RD., Patel R., Safdar MH., Jones HBL., Pinto-Fernandez A., Vendrell I., Chen H., Muli CS., Krabill AD., Kessler BM., Wendt MK., Das C., Flaherty DP.

DOI

10.1021/acs.jmedchem.3c01661

Type

Journal article

Publisher

American Chemical Society (ACS)

Publication Date

2024-03-28T00:00:00+00:00

Volume

67

Pages

4496 - 4524

Total pages

28

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