Resistance to malaria through structural variation of red blood cell invasion receptors

Leffler EM., Band G., Busby GBJ., Kivinen K., Le QS., Clarke GM., Bojang KA., Conway DJ., Jallow M., Sisay-Joof F., Bougouma EC., Mangano VD., Modiano D., Sirima SB., Achidi E., Apinjoh TO., Marsh K., Ndila CM., Peshu N., Williams TN., Drakeley C., Manjurano A., Reyburn H., Riley E., Kachala D., Molyneux M., Nyirongo V., Taylor T., Thornton N., Tilley L., Grimsley S., Drury E., Stalker J., Cornelius V., Hubbart C., Jeffreys AE., Rowlands K., Rockett KA., Spencer CCA., Kwiatkowski DP.

Structural variants are mapped that are correlated with a reduced risk of severe malaria.

DOI

10.1126/science.aam6393

Type

Journal article

Publisher

American Association for the Advancement of Science (AAAS)

Publication Date

2017-06-16T00:00:00+00:00

Volume

356

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