{ "items": [ "\n\n
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\n ASPP2 deficiency causes features of 1q41q42 microdeletion syndrome.\n

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\n \n Journal article\n \n

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Zak J. et al, (2016), Cell Death Differ, 23, 1973 - 1984

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\n Structure-function relationships of human JmjC oxygenases-demethylases versus hydroxylases.\n

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\n \n Journal article\n \n

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Markolovic S. et al, (2016), Curr Opin Struct Biol, 41, 62 - 72

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\n Restoring p53 Function in Human Melanoma Cells by Inhibiting MDM2 and Cyclin B1/CDK1-Phosphorylated Nuclear iASPP\n

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\n \n Journal article\n \n

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Lu M. et al, (2016), Cancer Cell, 30, 822 - 823

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\n p53 isoforms regulate astrocyte-mediated neuroprotection and neurodegeneration.\n

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\n \n Journal article\n \n

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Turnquist C. et al, (2016), Cell Death Differ, 23, 1515 - 1528

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\n Introducing STRaNDs: shuttling transcriptional regulators that are non-DNA binding.\n

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\n \n Journal article\n \n

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Lu M. et al, (2016), Nat Rev Mol Cell Biol, 17, 523 - 532

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\n Altered expression of epithelial-to-mesenchymal transition proteins in extraprostatic prostate cancer.\n

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\n \n Journal article\n \n

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Verrill C. et al, (2016), Oncotarget, 7, 1107 - 1119

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\n Caspase cleavage of iASPP potentiates its ability to inhibit p53 and NF-\u03baB.\n

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\n \n Journal article\n \n

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Hu Y. et al, (2015), Oncotarget, 6, 42478 - 42490

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\n Aspp1: A Guardian of Hematopoietic Stem Cell Integrity.\n

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\n \n Journal article\n \n

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Zak J. and Lu X., (2015), Cell Stem Cell, 17, 3 - 5

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\n iASPP, a previously unidentified regulator of desmosomes, prevents arrhythmogenic right ventricular cardiomyopathy (ARVC)-induced sudden death.\n

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\n \n Journal article\n \n

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Notari M. et al, (2015), Proc Natl Acad Sci U S A, 112, E973 - E981

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\n Applications of RNA interference high-throughput screening technology in cancer biology and virology.\n

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\n \n Journal article\n \n

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Gao S. et al, (2014), Protein Cell, 5, 805 - 815

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\n ASPP2 controls epithelial plasticity and inhibits metastasis through \u03b2-catenin-dependent regulation of ZEB1.\n

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\n \n Journal article\n \n

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Wang Y. et al, (2014), Nat Cell Biol, 16, 1092 - 1104

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\n Nuclear iASPP may facilitate prostate cancer progression.\n

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\n \n Journal article\n \n

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Morris EV. et al, (2014), Cell Death Dis, 5

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\n Restoring the tumour suppressive function of p53 as a parallel strategy in melanoma therapy.\n

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\n \n Journal article\n \n

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Lu M. et al, (2014), FEBS Lett, 588, 2616 - 2621

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\n Cancer: pathological nuclear reprogramming?\n

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\n \n Journal article\n \n

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Goding CR. et al, (2014), Nature Reviews Cancer, 14, 568 - 573

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\n STAT1-induced ASPP2 transcription identifies a link between neuroinflammation, cell polarity, and tumor suppression\n

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\n \n Journal article\n \n

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Turnquist C. et al, (2014), Proceedings of the National Academy of Sciences, 111, 9834 - 9839

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\n A code for RanGDP binding in ankyrin repeats defines a nuclear import pathway.\n

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\n \n Journal article\n \n

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Lu M. et al, (2014), Cell, 157, 1130 - 1145

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\n Siah2 regulates tight junction integrity and cell polarity through control of ASPP2 stability.\n

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\n \n Journal article\n \n

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Kim H. et al, (2014), Oncogene, 33, 2004 - 2010

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\n Structure of the Helicobacter pylori CagA oncoprotein bound to the human tumor suppressor ASPP2.\n

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\n \n Journal article\n \n

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Ne\u0161i\u0107 D. et al, (2014), Proc Natl Acad Sci U S A, 111, 1562 - 1567

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\n ASPP2 links the apical lateral polarity complex to the regulation of YAP activity in epithelial cells.\n

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\n \n Journal article\n \n

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Royer C. et al, (2014), PLoS One, 9

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\n Requirement for phosphorylation of P53 at Ser312 in suppression of chemical carcinogenesis.\n

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\n \n Journal article\n \n

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Slee EA. and Lu X., (2013), Sci Rep, 3

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