Dan Barouch : Novel HIV vaccine strategies
Professor Dan Barouch tells us about his time in Oxford, as a DPhil student in Professor Andrew McMichael's lab. He also comments on how we do as a field trying to develop HIV vaccines - overall not great since we don't have a vaccine yet, and we have tested only 3 conceps over the last 30 years.
Professor Barouch has demonstrated that cellular immune responses can partially control viral replication. This means that HIV-1 vaccines that generate potent cellular immune responses may provide important benefits even if they fail to afford sterilizing immunity. Professor Barouch has developed chimeric adenovirus vectors, and has advanced these vectors into preclinical studies and phase 1 clinical trials.
Professor Dan Barouch
HIV vaccines
Professor Dan Barouch is Director of the Center for Virology and Vaccine Research at Beth Israel Deaconess Medical Center, Harvard Medical School. After graduating from Harvard Medical School, Dan Barouch earned a DPhil in immunology at the University of Oxford. A world leader in the field of HIV research, Professor Barouch studies the immunology and virology of HIV-1 infection, and develops novel vaccine strategies for the virus. He leads a large programme that has developed a series of novel and promising HIV-1 vaccine candidates, which are currently in clinical trials, both in the USA and in sub-Saharan Africa.
Translational Medicine
From Bench to Bedside
Ultimately, medical research must translate into improved treatments for patients. At the Nuffield Department of Medicine, our researchers collaborate to develop better health care, improved quality of life, and enhanced preventative measures for all patients. Our findings in the laboratory are translated into changes in clinical practice, from bench to bedside.