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Research identifies how the gut loses protective barrier function in IBD

Research

A research team led by Prof Alison Simmons at MRC HIU and Professor of Gastroenterology used single-cell technology to identify new players in the gut epithelial barrier.

“By identifying new colonic epithelial cell types and uncovering fundamental determinants of barrier breakdown in IBD we open up avenues to restore the protective mucus layer pharmaceutically” said Prof Alison Simmons

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