Richard Maude

Graduate Research Prize Winners Autumn 2014

Richard Maude

As an undergraduate at the University of Edinburgh I obtained a BSc in Medical Parasitology and Entomology and graduated in Medicine with honours in 2000. Following junior doctor training in Edinburgh and Newcastle-Upon-Tyne and a LAT in Oxford I commenced specialty training in Tropical Medicine and General (Internal) Medicine in 2004 in Birmingham. I was Associate Clinical Director of Acute Medicine at Heartlands Hospital in Birmingham from 2005-2006 following which I worked as a Specialist Registrar in Darwin, Australia. I completed a Diploma of Tropical Medicine and Hygiene with Distinction and was awarded the Warrington-Yorke medal at Liverpool School of Tropical Medicine in 2007. Since 2007, I have worked at Mahidol-Oxford Tropical Medicine Research Unit, Bangkok, Thailand where I studied for my DPhil.

My DPhil title was “Malaria Elimination Modelling in the Context of Antimalarial Drug Resistance”. For this I conducted clinical and epidemiological studies on malaria incidence and artemisinin resistance in South and Southeast Asia and developed population level mathematical models of malaria treatment, antimalarial drug resistance and malaria elimination in Cambodia and Bangladesh. These models helped guide policy decisions for strategies to tackle artemisinin resistance and for malaria elimination. In parallel, I was principal and co-investigator for a series of clinical studies on the pathogenesis and treatment of severe malaria in Bangladesh and India.

I am currently a senior clinical research fellow at the University of Oxford, honorary consultant physician at the John Radcliffe Hospital in Oxford and visiting scientist at Harvard School of Public Health. Based at Mahidol-Oxford Tropical Medicine Research Unit, my research combines clinical studies, descriptive epidemiology and mathematical modelling of malaria in South and Southeast Asia. My areas of interest include population dynamic mathematical modelling of artemisinin resistance and malaria elimination; spatiotemporal epidemiology, GIS mapping and population movement; as well as clinical studies on artemisinin resistance, observational studies on pathogenesis, malaria retinopathy and medical imaging in severe malaria; clinical trials of treatment and supportive care for severe malaria and diagnosis of non-malaria causes of fever. I work with collaborators in Australia, Bangladesh, Cambodia, India, Malaysia, Myanmar, Thailand, the USA and the UK.

Publications

Maude RJ, Nguon C, Dondorp AM, White LJ, White NJ. The diminishing returns of atovaquone-proguanil for elimination of Plasmodium falciparum malaria: modelling mass drug administration and treatment. Malar J. 2014;13:380.

Maude RJ, Ahmed BUMW, Rahman AHMW, Rahman R, Majumder MI, Braganza Menezes D, Abu Sayeed A, Hughes L, MacGillivray TJ, Borooah S, Dhillon B, Dondorp AM, Faiz MA. Retinal Changes in Visceral Leishmaniasis by Retinal Photography. BMC Infect Dis. 2014;14:527.

Maude RJ, Nguon C, Ly P, Bunkea T, Ngor P, Canavati de la Torre S, White NJ, Dondorp AM, Day NPJ, White LJ, Meng Chuor C. Spatial and Temporal Epidemiology of Clinical Malaria in Cambodia 2004-2013. Malar J. 2014;13:385.