Seminars

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Tue 29 May 2018 from 13:00 to 14:00

Molecular Haematology Unit, WIMM

MRC Weatherall Institute of Molecular Medicine, Seminar Room, Headington OX3 9DS

Novel metabolic regulators of haematopoietic stem cell biology and leukaemic transformation

Kamil Kranc

Audience: Members of the University only

Organisers: Liz Rose

Tue 29 May 2018 from 13:00 to 14:00

Population Health Seminars

Richard Doll Building, Richard Doll Lecture Theatre, Old Road Campus OX3 7LF

Richard Doll Seminar - Diabetes No More! Results from the DiRECT trial

Professor Mike Lean

Professor Mike Lean trained in medicine at Cambridge University and St Barts Hospital, London, before taking up the position of MRC Clinical Scientist in the Cambridge University Dunn Nutrition Unit. In his present position at the University of Glasgow, since 1993, he established the Department of... Read more

Professor Mike Lean trained in medicine at Cambridge University and St Barts Hospital, London, before taking up the position of MRC Clinical Scientist in the Cambridge University Dunn Nutrition Unit. In his present position at the University of Glasgow, since 1993, he established the Department of Human Nutrition. It is based on a ‘broad-focus’ strategy toward translational, integrative, research and teaching, encompassing the full range of scientific disciplines within Human Nutrition: basic sciences, epidemiology, clinical studies and community/population-directed interventions. As well as scientific work, outputs include regular writing for the general public in newspapers and TV for Public Understanding of Science. In this seminar he will discuss the rationale for, and results of, the DiRECT trial which was supported by the biggest research grant ever awarded by Diabetes UK. DiRECT was conducted in primary care and compared an intensive weight loss programme to best-practice care in patients with type 2 diabetes. Remission of diabetes occurred in nearly half the patients allocated to the weight loss programme.

Audience: Members of the University only

Organisers: Graham Bagley

Wed 30 May 2018 from 10:30 to 11:30

Nuffield Department of Primary Care Health Sciences - Department research seminars

St Luke's Chapel, Woodstock Road OX2 6GG

NIHR CLAHRC OXford

Gavin Hubbard, Dr Esther Williamson

Find out more about what the NIHR CLAHRC Oxford is and what it does, with a special emphasis on how we're working to implement interventions proven in clinical trials in the real-world NHS. Dr Esther Williamson of the 'Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences'... Read more

Find out more about what the NIHR CLAHRC Oxford is and what it does, with a special emphasis on how we're working to implement interventions proven in clinical trials in the real-world NHS. Dr Esther Williamson of the 'Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences' will talk about her findings and work developing online tools for training patients and therapists in two clinically proven and NICE recommended interventions: 1) iBeST a group-based cognitive behavioural intervention for low back pain, the leading cause of disability worldwide, that has been shown to significantly reduce disability and pain compared to conventional treatments, and for longer; and 2) the SARAH programme, a proven and effective exercise-based therapy used alongside drugs to treat rheumatoid arthritis (RA) of the hand.

Audience: Members of the University only

Organisers: Dr Jenny Hirst

Wed 30 May 2018 from 11:00 to 12:00

Strubi seminars

Wellcome Trust Centre for Human Genetics, Meeting rooms A & B, Headington OX3 7BN

"Structure and assembly in the order Picornavirales"

Dr Shabih Shakeel

The order Picornavirales comprises of several virus families which infect humans, animals and insects. Even though all viruses in this order are icosahedrally-symmetric and are made of three capsid proteins, there are several distinct features found in their capsids. Additionally, the capsid... Read more

The order Picornavirales comprises of several virus families which infect humans, animals and insects. Even though all viruses in this order are icosahedrally-symmetric and are made of three capsid proteins, there are several distinct features found in their capsids. Additionally, the capsid assembly was thought to be conserved across virus families. However, our recent work suggests otherwise. I will discuss two examples, human parechovirus (family: Picornaviridae) and norovirus (family: Dicistoviridae) from the order Picornavirales whose structures and assemblies do not follow not so common path.

Audience: Members of the University only

Organisers: Agata Krupa

Thu 31 May 2018 from 11:00 to 12:00

Ludwig Institute Seminar Series

NDM Building, Basement seminar room, TDI, Headington OX3 7FZ

Modern Pathology Platforms to Support Basic and Translational Research

Professor Manuel Salto-Tellez

Molecular Pathology is the interrogation of clinical samples to a) understand better the nature of diseases; or b) to diagnose, prognosticate or decide on therapeutic intervention of diseases. As such, it is a relevant component of basic and translational research operations. This lecture will... Read more

Molecular Pathology is the interrogation of clinical samples to a) understand better the nature of diseases; or b) to diagnose, prognosticate or decide on therapeutic intervention of diseases. As such, it is a relevant component of basic and translational research operations. This lecture will provide examples on how Molecular Pathology has helped in the generation of laboratory information to support hypothesis on molecular mechanisms of disease, or to understand the clinical relevance of basic science discoveries. In the process, we will discuss the technical approaches to these applications and how molecular pathology can be integrated in research institutes to facilitate discovery and translation.

Audience: Members of the University only

Organisers: Christina Woodward

Thu 31 May 2018 from 13:00 to 14:00

Medical Grand Rounds

John Radcliffe Academic, Lecture Theatre 1, Headington OX3 9DU

Radiology / Neurology

Dr Chrystallina Antoniades

Radiology: -- Neurology: "The OxQUIP study", Dr Chrystallina Antoniades -- Chair: Prof Chris Conlon

Radiology: -- Neurology: "The OxQUIP study", Dr Chrystallina Antoniades -- Chair: Prof Chris Conlon

Audience: Public

Audience: Members of the University and NHS clinical staff.