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Chris Garrard

Dr, Clinical Lecturer in Intensive Care

UK Critical Care Genomics (UKCCG) A consortium of 30 UK Intensive Care Units collaborating in genomic studies of host response to severe life threatening infection. Leads: Dr CS Garrard (NDM) and Prof Charles Hinds (St Bartholomew's Hospital, London) see: http://www.ukccg-gains.org/

UKCCG currently participating in 2 large, multi-centre genome association studies in the UK (Genomic Advances in Sepsis - GAinS) and in Europe (Genetics of Sepsis - GenOSept). Funded by the Sainsbury Charitable Fund and 6th Framework programme of Research and Development - European Union) these studies are actively recruiting patients with sepsis syndrome admitted to Intensive Care Units in the UK and Europe with admission diagnoses of community acquired pneumonia, faecal peritonitis (GAinS) pancreatitis or meningococcal disease (GenOSept).  See also:  https://clinicaltrials.gov/

Recent publications

Shared and Distinct Aspects of the Sepsis Transcriptomic Response to Fecal Peritonitis and Pneumonia

Journal article

Burnham KL. et al, (2017), American Journal of Respiratory and Critical Care Medicine, 196, 328 - 339

Genomic landscape of the individual host response and outcomes in sepsis: a prospective cohort study

Journal article

Davenport EE. et al, (2016), The Lancet Respiratory Medicine, 4, 259 - 271

Variants in the Mannose-binding Lectin GeneMBL2do not Associate With Sepsis Susceptibility or Survival in a Large European Cohort

Journal article

Mills TC. et al, (2015), Clinical Infectious Diseases, 61, 695 - 703

More publications