Inoculation of New World primates with the human immunodeficiency virus.

McClure MO., Schulz TF., Tedder RS., Gow J., McKeating JA., Weiss RA., Baskerville A.

The susceptibility of common marmosets and cotton-top tamarins to infection by HIV-2 in vivo was tested. One year and 19 months, respectively, post-inoculation, sera taken from three of four animals from each species are reactive for HIV-2 antibodies and HIV-specific nucleotide sequences were demonstrated in short-term cultures of PBL from two cotton-top tamarins. The animals remain in good health.

DOI

10.1111/j.1600-0684.1989.tb00235.x

Type

Journal article

Publication Date

1989-01-01T00:00:00+00:00

Volume

18

Pages

329 - 335

Total pages

6

Addresses

Institute of Cancer Research, Chester Beatty Laboratories, London, England.

Keywords

Animals, Cebidae, Aotus trivirgatus, Callitrichinae, Callithrix, Saguinus, HIV-1, HIV-2, Acquired Immunodeficiency Syndrome, Disease Models, Animal, DNA, Viral, HIV Antibodies, Blotting, Western, Enzyme-Linked Immunosorbent Assay, Blotting, Southern, Nucleic Acid Hybridization

Permalink More information Close