Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences

Martinez FO., Helming L., Milde R., Varin A., Melgert BN., Draijer C., Thomas B., Fabbri M., Crawshaw A., Ho LP., Ten Hacken NH., Cobos Jiménez V., Kootstra NA., Hamann J., Greaves DR., Locati M., Mantovani A., Gordon S.

Key PointsHuman and mouse macrophages share partially conserved gene and protein expression programs in the resting or M2 activated state. TGM2 is a novel M2 marker consistently induced in human and mouse M2 macrophages.

DOI

10.1182/blood-2012-06-436212

Type

Journal article

Publisher

American Society of Hematology

Publication Date

2013-02-28T00:00:00+00:00

Volume

121

Pages

e57 - e69

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