Hepatitis B reactivation following switch away from tenofovir-containing anti-retroviral therapy in people living with HIV: A case series and lessons for practice
Olcott F., Oddie PD., Barlow MJ., Mamarelis A., Byott M., Grant P., Botha J., Booth C., Waters L., Matthews PC., Flanagan S., Nastouli E., Ghosh I.
Abstract The potential for hepatitis B reactivation must be considered when switching people with HIV and prior hepatitis B exposure away from tenofovir-containing combined anti-retroviral therapy. Four cases of hepatitis B reactivation from the United Kingdom are presented. Hepatitis B mutations, risk factors and pre- and post-switch recommendations are explored.