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News

The latest news, research updates and announcements from the Nuffield Department of Medicine.

For media enquiries, background information on any of our research, or to arrange interviews with relevant scientists please contact Marin Hirschfeld, NDM Head of Communications. We also have photos and videos of our work available for B-roll purposes.

What's new

New malaria study to support WHO guideline changes

Publications & research news

Researchers from the Centre for Tropical Medicine and Global Health at NDM have contributed to a new study which will help inform World Health Organization guidelines for treating children with Plasmodium vivax malaria. They found that giving children higher doses of primaquine substantially reduced recurrences of malaria.

Pseudouridine landscape across the human transcriptome mapped

Publications & research news

The Song group at Ludwig Oxford in the Nuffield Department of Medicine have published a technique for mapping the pseudouridine landscape across the human transcriptome.

New GSK collaboration will develop use of biostatistics and AI in research

Departmental news & awards

With a base in the University's Nuffield Department of Medicine and Department of Statistics, the collaboration will draw upon biostatistical and artificial intelligence (AI) expertise across Oxford, prioritising the development of innovative new tools and methods that translate to medical and biopharmaceutical research.

Youth ambassadors raise tetanus awareness through public engagement activities

Departmental news & awards

The Youth Science Ambassadors (YSA) project has become key in the youth engagement activities of OUCRU’s Public and Community Engagement Group. Becoming part of the project, young participants are empowered to lead, propose, plan, and execute their own initiatives addressing specific issues they identify themselves.

Inflammation stimulates antimicrobial peptide release for epithelial defence

Publications & research news

The Boccellato group at NDM’s Ludwig Institute for Cancer Research have studied the regulation of antimicrobial peptide secretion in the mucus and its role in determining the colonisation of a pathogen association with stomach cancer.

New point-of-care testing to improve antibiotic use in Vietnam

Publications & research news

High levels of acceptability for a point-of-care testing service to improve antibiotic distribution for in Vietnamese pharmacies have been discovered by the Oxford University Clinical Research Unit (OUCRU), part of the Nuffield Department of Medicine.

Dr Lennard Lee wins 2024 Government Science and Engineering award

Departmental news & awards

The UK Government’s Science and Engineering award recognises teams or individuals who have made a significant achievement in delivering major national flagship scientific or engineering initiatives.

Improving survival rates of children with sickle cell disease in Kenya

Publications & research news

Research on sickle cell disease conducted by KEMRI-Wellcome Trust Research Programme (KWTRP) at the Nuffield Department of Medicine shows significant progress in understanding how to improve survival rates and quality of life for those living with the condition.

Central Ho Chi Minh City identified as a hotspot for tuberculosis

Publications & research news

A recent study identified key factors contributing to the tuberculosis burden in Ho Chi Minh City, conducted by researchers from the Oxford University Clinical Research Unit in Vietnam (OUCRU), part of the Nuffield Department of Medicine, and Pham Ngoc Thach Hospital.

Antibiotic resistance could cause 39 million deaths between now and 2050

Publications & research news

Based on estimates across 204 countries and territories, new forecasts from the Global Research on Antimicrobial Resistance (GRAM) Project suggest that bacterial antimicrobial resistance (AMR) will cause 39 million deaths between 2025 and 2050 – equating to three deaths every minute.

Hydroxychloroquine provides moderate COVID-19 prevention

Publications & research news

Four years after being derailed by scientific fraud and politicised science in the first year of the pandemic, COPCOV, the world’s largest COVID-19 chemoprevention study, finally published results today that showed that hydroxychloroquine (HCQ) does have a moderate benefit in preventing COVID-19.

Improving understanding of lung microbiome in severe asthma patients

Publications & research news

Researchers in the Nuffield Department of Medicine, supported by NIHR Oxford Biomedical Research Centre (BRC), have discovered a link between potentially pathogenic bacteria and airways inflammation in people with severe asthma.

Developing the first cancer prevention vaccine for Lynch syndrome

News

Scientists from the Centre for Human Genetics at Nuffield Department of Medicine are taking the initial steps in developing the UK’s first vaccine to prevent cancer in people with Lynch syndrome, thanks to funding from Cancer Research UK.

Adoptive T cell therapy shows an enhanced tumour response

Publications & research news

The Van den Eynde groups at the Ludwig Institute for Cancer Research in Brussels and Oxford have demonstrated that deletion of PHD2/3 enzymes in CD8 T cells shows an enhanced tumour response in various cancer models.

Preventive vaccination could be a key strategy against Lassa fever

Publications & research news

Researchers at the University of Oxford and the University of Liverpool have for the first time been able to estimate the current burden of Lassa fever, project the impacts of a Lassa fever vaccination programme, and demonstrate how it may help avoid the next pandemic.

Scientists develop new method to detect fake vaccines

Publications & research news

Scientists have developed a first-of-its-kind mass spectrometry method for vaccine authenticity screening using machine learning. The method repurposes clinical mass spectrometers already present in hospitals worldwide, making the approach feasible for global supply chain monitoring. The discovery offers an effective solution to the rise in substandard and counterfeit vaccines threatening public health.

Ten NDM researchers awarded full professorships

Departmental news & awards

We are delighted to announce that ten researchers have been awarded the title of Professor, in recognition of their research achievements, contribution to teaching, and contribution to the general work of the Nuffield Department of Medicine.

OUCRU and Universitas Indonesia complete historic malaria vaccine trial

Publications & research news

The Faculty of Medicine Universitas Indonesia (FMUI) and OUCRU Indonesia have completed a phase 2 clinical trial for two new malaria vaccines developed by Sanaria Inc. This is the first malaria vaccine trial ever conducted in Indonesia and the first in the Asia-Pacific region in over 30 years.

PSI collaborates with Oxford's History of Science Museum on new exhibition

News

The Pandemic Sciences Institute, in collaboration with the Ethox Centre, has supported a new exhibition at Oxford’s History of Science Museum. The exhibition, entitled "A Healthy Future for All?", explores the science driving advancements in healthcare