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News

The latest news, research updates and announcements from the Nuffield Department of Medicine.

For media enquiries, background information on any of our research, or to arrange interviews with relevant scientists please contact Marin Hirschfeld, NDM Head of Communications. We also have photos and videos of our work available for B-roll purposes.

What's new

New insights into mpox clinical outcomes and transmission

Results of MOSAIC, a European observational study led by researchers at PSI and ISARIC, provides evidence on how the clade IIb mpox virus affects patients and the risks of onward transmission.

Unlocking cellular symmetry could revolutionise understanding of disease

Led by Professor Yvonne Jones at the Division of Structural Biology and Professor David Strutt at the University of Sheffield's School of Biosciences, this £3.7 million Wellcome Trust-funded project brings together cutting-edge technology and world-class expertise.

New funding to create a lymphoid organoid and explant hub received

Dr Pablo F. Céspedes, CAMS Oxford Institute Career Development Fellow, has received funding from NC3Rs to establish a lymphoid organoid and explant hub for researchers across the country.

The Global Health Network reaches 1 million members

The Global Health Network has achieved a remarkable milestone: one million members worldwide. This dynamic and inclusive community of healthcare professionals and researchers is addressing two of the most pressing challenges in global health. By equipping teams to tackle everyday diseases of poverty and strengthening the ability to detect and respond to emerging threats, The Global Health Network is saving lives and safeguarding the future of global health.

Researchers discover new way to target cancer and immune-related diseases

Groundbreaking research by scientists from the Centre for Medicines Discovery at the Nuffield Department of Medicine opens up new possibilities for developing treatments that could both fight cancer and regulate the immune system, offering hope for better and more precise therapies in the future.

Professor Sarah Gilbert appointed as Deputy Head of Department

The Department wishes to announce that Professor Dame Sarah Gilbert has been appointed to the role of Deputy Head of Department of the Nuffield Department of Medicine for a five-year term.

Inhaled vaccines could reduce viral transmission

An important step toward advancing vaccines for human use, a recent study has shown that inhaled vaccines could potentially improve efficiency and reduce viral transmission.

New blood test could enable early detection of multiple cancers

A new blood test – powered by machine learning – has shown real promise in detecting multiple types of cancer in their earliest stages, when the disease is hardest to detect. Developed by a team of researchers and co-lead by the Centre for Human Genetics’ Dr Dimitris Vavoulis, the test accurately detected six cancer types and could distinguish between people with and without cancer.

Ben Schuster-Böckler elected as a Fellow of the Royal Society of Biology

The Royal Society of Biology have recognised Associate Professor Benjamin Schuster-Böckler from NDM's Ludwig Institute for Cancer Research as a Fellow in their January 2025 nominations round.

Optimising testing for disease surveillance with machine learning

A new machine learning-informed strategy could support public health leaders to design better disease surveillance during a disease outbreak.

Certain antimalarial drugs show moderate effect in preventing COVID-19

Mahidol Oxford Tropical Medicine Research Unit (MORU) have led the world’s largest study on the use of hydroxychloroquine and chloroquine to prevent COVID-19. With results showing moderate protection against the virus, the trial involved over 4,600 participants and found a 15% reduction in symptomatic COVID-19 among those who took the medications compared to those who took a placebo.

Study on the impact of protein modification on cell physiology receives £6.4m

A study aimed at increasing understanding of how cells function has received funding of £6.4 million. Led by the University of Strathclyde, NDM’s Division of Structural Biology (STRUBI) and collaborators from other universities across the UK will be working together to increase understanding in this area of research.

Dr Lennard Lee featured in Fujifilm anniversary documentary series

NDM’s Dr Lennard Lee has been featured in Fujifilm Europe’s 90th Anniversary celebration documentary series, which honours 20 exceptional innovators helping to shape the future across Europe. Dr Lee has been recognised as a UK exemplar for his groundbreaking contributions to the cancer vaccines research field, accelerating the uptake of digital trials, and demonstrating a faster, simpler, and more efficient model for clinical trials.

Reversing resistance to cancer immune therapy with antibodies

A new study led by Professor Ignacio Melero of NDM's Centre for Immuno-oncology and the University of Navarra and has highlighted a way to combat resistance to cancer immunotherapy in solid tumours by using antibodies that target GDF-15 protein.

Launch of largest-ever study tracking chikungunya burden in East Africa

A team of scientists in the UK, Kenya and Tanzania will soon find out the extent to which chikungunya, a debilitating mosquito-borne disease causing large outbreaks in Asia and South America, is also affecting countries in East Africa.

Prof Anneke Lucassen to lead Public and Community Engagement with Research

Professor Anneke Lucassen will chair the Public and Community Engagement with Research Advisory Board and launch the 2024-2029 strategy as the new Academic Champion for Oxford University.

Two new MRC Centres to create cutting-edge gene therapies

The Medical Research Council (MRC), part of UKRI, is launching its first two Centres of Research Excellence (CoRE), which will develop transformative new advanced therapeutics for currently untreatable diseases. Oxford is leading one of these Centres and co-leading the other. Together, these international collaborations will receive up to £50 million each over 14 years.

Md Zakiul Hassan recognised as 2024 ISID Emerging Leader

PSI researcher Md Zakiul Hassan, the inaugural Oxford-MoH Foundation DPhil Scholar, has been recognised as 2024 ISID Emerging Leader in International Infectious Diseases. The award from the International Society for Infectious Diseases acknowledges early-career excellence in the field.

Dr Xin Hui Chan awarded BIA Barnett Christie Lecture

Dr Xin Hui Chan has won the competitive 2024 Barnett Christie Lecture award of the British Infection Association. As part of the award, Dr Chan delivered a lecture entitled ‘Drugs for Tropical Infections: Challenges, Opportunities, and the Infectious Disease Physician’.

New iontronic platform could advance miniature cancer-treatment systems

Researchers at NDM’s Ludwig Cancer Research, the École Polytechnique Fédérale de Lausanne and other Oxford departments report the use of surfactant-supported assembly of freestanding microscale hydrogel droplets to construct iontronic modules and biointerfaces.