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News

The latest news, research updates and announcements from the Nuffield Department of Medicine.

For media enquiries, background information on any of our research, or to arrange interviews with relevant scientists please contact Marin Hirschfeld, NDM Head of Communications. We also have photos and videos of our work available for B-roll purposes.

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What's new

Using a microscope for cancer research in a lab

Molecule enabling new leukaemia treatments discovered

Researchers at the Shi Lab have discovered a first-in-class LSD1 PROTAC degrader, which opens up new therapeutic paths for the treatment of acute myeloid leukaemia. PROTAC degraders are molecules that degrade proteins by using the cell’s own machinery, binding to both the target protein and an E3 ligase, which marks it for degradation by the proteasome.

Eight NDM researchers awarded Associate Professorships

We are delighted to announce that eight researchers have been awarded the Associate Professor title, in recognition of their research achievements, contribution to teaching, and contribution to the general work of the Nuffield Department of Medicine.

Professor François Nosten, SMRU Director; Dr Pitakpong Chandang, Tak Provincial Chief Medical Officer; Dr Sutha Phatrakitrungruang, Mae Ramat Hospital Director

Oxford and Thai health officials sign agreement on infectious disease control

Representatives from the University of Oxford and the Tak Provincial Public Health Office signed a Memorandum of Understanding (MoU) to strengthen collaboration on infectious disease prevention and control along the Thai–Myanmar border. The agreement focuses on joint research into key diseases affecting the border population.

T cell responses to monkeypox play a part in protecting against infection

A new study, led by researchers at the NDM's CAMS Oxford Institute and the Centre for Human Genetics, TIDU in the MRC Weatherall Institute of Molecular Medicine, the Kennedy Institute and the Dunn School of Pathology, has found that specific T cells could have an impact on the long-term protective responses to future infection.

More effective and affordable treatment strategies for Hepatitis C

NDM's Oxford University Clinical Research Unit (OUCRU) announced promising results from the VIETNARMS trial, a years-long multi-arm clinical trial conducted in Vietnam. The trial found that the readily available and affordable Hepatitis C treatment sofosbuvir/daclatasvir had a >95% cure rate. The results offer important insights into new treatment regimens for Hepatitis C, potentially reducing treatment durations and halving treatment costs.

Professor Yang Shi wins 2025 Léopold Griffuel Prize

Professor Yang Shi wins 2025 Léopold Griffuel Prize

The ARC Foundation for Cancer Research has recognised Professor Yang Shi’s contributions to the field of cancer epigenetics with the 2025 Léopold Griffuel Prize for Fundamental Research.

Coeliac disease may be driven by immune structures in the gut

Researchers in the Nuffield Department of Medicine have found structures of immune cells in the gut that may be driving the response to gluten in people with coeliac disease. These findings could provide a target for future therapies.

Prof Andrew McMichael

Professor Andrew McMichael elected to the US National Academy of Sciences

The National Academy of Sciences (NAS) in the US just announced the election of 120 members and 30 international members in recognition of their distinguished and continuing achievements in original research. Election to membership in the NAS is a mark of excellence in science and considered one of the highest honours that a scientist can receive.

Person holding stomach

New guidelines published for monitoring IBD patients to prevent bowel cancer

Led by NDM’s Professor James East, researchers and clinicians have developed major new guidelines for monitoring patients with inflammatory bowel disease (IBD) to prevent them going on to develop bowel cancer.

Doctor checking a mole

Common virus may improve skin cancer treatment outcomes

May is Skin Cancer Awareness Month, and a new study with input from researchers in NDM’s units has revealed that a common virus may positively influence how skin cancer patients respond to current treatments.

Mother giving child medicine

New study confirms malaria drug safe for children and reduces disease burden

A major study in The Lancet Infectious Diseases confirms that single low-dose primaquine is safe and effective in reducing malaria transmission in young children. Analysing data from over 6,000 patients, researchers found it effective even in young children and areas with high malaria burden.

Blog: Building better vaccines in Thailand

Years of groundwork have led Assistant Professor Dr Thitinan Kitisin to his first major step: leading an advanced vaccine research project in Thailand. With support from MODRA, he’s now developing one of the first tonsil organoid models in the country, a small but important step toward improving how vaccines are tested. Along the way, he’s also passing on practical research skills to the next generation of Thai scientists.

Celebrating 10 years of the MSc in International Health and Tropical Medicine

NDM's MSc in International Health and Tropical Medicine (IHTM) celebrated its tenth anniversary as an internationally renowned programme for future global health leaders, with over 100 alumni travelling from around the world to join colleagues, current students and guests in Oxford.

Study finds that Treg depletion suppresses tumour growth

A new study, co-lead by Dr Felipe Galvez-Cancino from the Centre for Immuno-Oncology, has shown that Treg cell depletion can suppress tumour growth in one of the deadliest types of cancer.

Professor Dame Sarah Gilbert, PSI, NDM

Sarah Gilbert receives Royal Society of Chemistry Honorary Fellowship

PSI Principal Investigator Professor Dame Sarah Gilbert has been made an Honorary Fellow of the Royal Society of Chemistry.

Professor Buddha Basnyat

Professor Buddha Basnyat recognised by the Nepal Health Research Council

Professor Buddha Basnyat has received the NHRC Lifetime Achievement Award for Health Research in Nepal. The Nepal Health Research Council (NHRC) recently conferred its prestigious Lifetime Achievement Award for Health Research upon Professor Basnyat at the 11th National Summit of Health and Population Scientists. This honour recognises his exceptional contributions to medical research and public health over a career spanning more than five decades.

cancer research in lab

New combination therapy developed for acute myeloid leukaemia

Researchers in the Shi group at Ludwig Cancer Research Oxford have developed a new combination therapy for acute myeloid leukaemia, showing therapeutic promise by promoting differentiation of immature blood cells.

Dr Sulochana Manandhar

Blog: Tackling newborn infection risks in Nepal

At OUCRU Nepal, microbiologist Sulochana Manandhar spent much of her early career at the lab bench, examining bacteria, fine-tuning methods, and chasing answers to scientific questions. Now, with support from the MODRA programme, she’s leading her first hospital-based study, bringing new attention to neonatal health risks in Nepal.

Woman using asthma inhaler

Study identifies direct link between inflammation and asthma attacks

An international consortium of respiratory scientists, including researchers from NDM’s Experimental Medicine Division, have shed light on the role of inflammation in asthma. Through their findings, they have provided a new way of predicting and preventing asthma attacks.

Up to £16.5 million awarded to global consortium to overcome obstacles in infectious disease research

The International Severe Acute Respiratory and emerging Infection Consortium (ISARIC) has been awarded up to £16.5 million to build on its globally-recognised efforts to prevent illness and deaths from epidemic-prone infectious diseases.