The department supports investigator-led research through a series of well-founded laboratories. This research covers every aspect of biological science related to medicine: from the bench to the bedside, from blue sky to full clinical trials, from technology development to spin-out. It covers many fields and many clinical disciplines.
The department supports this research in an environment designed to foster the long-term career development of fellows and research staff.
All of the above is made possible through the generosity and long-term support of our sponsors and funders.
Public Health England achieved a world’s first this March by rolling-out a routine diagnostic service for mycobacterial infections that is based on whole-genome sequencing (WGS) developed by a team led by Professor Derrick Crook. The change is likely to impact how clinicians manage their patients and how public health control disease. After over 130 years of culture-based bacteriology, this feels like the beginning of a long overdue paradigm shift to a new, sequencing-based era.
Viral hepatitis is one of the leading causes of death and disability worldwide. Led by Professor Ellie Barnes and Dr Chris Spencer, NDM researchers within STOP-HCV have developed high-throughput laboratory and computational tools to generate and analyse genetic data from hundreds of patients and the Hepatitis C virus that infects them. The analysis has given us new insights into the specific host genes that shape the viral genome and replication.