The department supports investigator-led research through a series of well-founded laboratories. This research covers every aspect of biological science related to medicine: from the bench to the bedside, from blue sky to full clinical trials, from technology development to spin-out. It covers many fields and many clinical disciplines.
The department supports this research in an environment designed to foster the long-term career development of fellows and research staff.
All of the above is made possible through the generosity and long-term support of our sponsors and funders.
Chronic obstructive pulmonary disease (COPD) is a common chronic lung disease associated with significant illness. Eosinophilic inflammation (immune cells usually associated with allergy) can help to inform us about which treatments will work the best in our patients with COPD according to research by Prof Mona Bafadhel, recently published in the Lancet.
Professor Gil McVean and colleagues have released new methodology for using vast genomic data sets to map how variation in factors such as drug treatment or immune repertoire influences within-patient HIV-1 evolution. This work provides greatly enhanced resolution for characterising key viral processes including drug- and immune-escape.