Research

Research

Research in NDM

The department supports investigator-led research through a series of well-founded laboratories. This research covers every aspect of biological science related to medicine: from the bench to the bedside, from blue sky to full clinical trials, from technology development to spin-out. It covers many fields and many clinical disciplines.

Researchers

The department supports this research in an environment designed to foster the long-term career development of fellows and research staff.

All of the above is made possible through the generosity and long-term support of our sponsors and funders.

Research Highlights

Activation and In Vivo Evolution of the MAIT Cell Transcriptome in Mice and Humans Reveals Tissue Repair Functionality

Activation and In Vivo Evolution of the MAIT Cell Transcriptome in Mice and Humans Reveals Tissue Repair Functionality

Posted 20/09/2019

Dr Timothy Hinks, from NDM'S Experimental Medicine Division led one of two research groups studying these cells. The research was also supported by the NIHR Oxford Biomedical Research Centre.  These cells could be harnessed to help heal tissues and treat diseases such as infections of the lung, the bowel or the skin.  Dr Hinks said: MAIT cells are remarkable in several ways. They are very numerous throughout the different tissues of our bodies. They are also ancient in evolutionary terms, being found in animals as distantly related as humans, mice and even opossums and Tasmanian devils. 

Leveraging genetics to help inform drug target discovery

Leveraging genetics to help inform drug target discovery

Posted 28/06/2019

A new study led by Professor Julian Knight at the Wellcome Centre for Human Genetics and colleagues from the ULTRA-DD Consortium shows how genetics and knowledge of networks can prioritise drug targets for immune-mediated diseases. The Priority Index pipeline developed by first-author Dr Hai Fang is published in Nature Genetics.

 

 

Research Highlights archives