The department supports investigator-led research through a series of well-founded laboratories. This research covers every aspect of biological science related to medicine: from the bench to the bedside, from blue sky to full clinical trials, from technology development to spin-out. It covers many fields and many clinical disciplines.
The department supports this research in an environment designed to foster the long-term career development of fellows and research staff.
All of the above is made possible through the generosity and long-term support of our sponsors and funders.
Disease processes can switch genes on or off in a cell and this can alter the progress of the disease. In studying the control of immune genes, Chris O’Callaghan and colleagues have discovered a new form of regulation in human genes—interacting control elements within an individual gene can flip the switch on the gene in the opposite direction to that expected.