viremia 10 Years Postdiscontinuation of Antiretroviral Therapy Initiated During Primary Human Immunodeficiency Virus-1 Infection and Association With Gag-Specific T-Cell Responses
Kinloch-de Loes S., Dorrell L., Yang H., Hardy GAD., Yerly S., Cellerai C., Vandekerckhove L., De Spielgelaere W., Malatinkova E., Wee Lee Koh W., Johnson MA.
Abstract Combination antiretroviral therapy during primary human immunodeficiency virus-1 infection may enable long-term drug-free virological control in rare individuals. We describe a female who maintained aviremia and a normal CD4+/CD8+ T cell ratio for 10 years after stopping therapy, despite a persistent viral reservoir. Cellular immune responses may have contributed to this outcome.