Cotrimoxazole reduces systemic inflammation in HIV infection by altering the gut microbiome and immune activation
Bourke CD., Gough EK., Pimundu G., Shonhai A., Berejena C., Terry L., Baumard L., Choudhry N., Karmali Y., Bwakura-Dangarembizi M., Musiime V., Lutaakome J., Kekitiinwa A., Mutasa K., Szubert AJ., Spyer MJ., Deayton JR., Glass M., Geum HM., Pardieu C., Gibb DM., Klein N., Edens TJ., Walker AS., Manges AR., Prendergast AJ.
Cotrimoxazole reduces systemic and intestinal inflammation in HIV infection by suppressing gut-resident Streptococci and immune cell activation.