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john-stradling

Contact information


john.stradling@ouh.nhs.uk


Churchill Hospital

John Stradling

Obstructive sleep apnoea (OSA):-

  • Epidemiology
  • Cardiovascular consequences of OSA
  • Diabetes/retinopathy
  • Symptoms
  • Clinical mangement

Current main project is a multicentre trial of CPAP in patients with OSA and diabetic macular oedema, funded by the ResMed foundation. In addition we have used a CPAP withdrawal model to look at oxidative stress in OSA, funded by British Heart Foundation. A cross-sectional study of ventilatory failure in obesity has been recently completed. The CPAP withdrawal model is being used to look at vascular reactivity in the eye and the relevance of intermittent hypoxia to the cardiovascular effects in OSA.