Postdoctoral Research Scientist - Epigenetics

Ludwig Institute for Cancer Research, NDM Research Building, Old Road Campus, Headington, Oxford

Applications to be received by 12pm on Friday 5th of July 2019

Grade 7: £32,236- £39,609 p.a.

We are seeking to appoint a Postdoctoral Research Scientist to join Dr Chunxiao Song’s research group located at the NDM Research Building. The role will be helping to develop technologies in epigenetics and applying them to elucidate epigenetic mechanisms in tumour biology and develop clinical applications in epigenetics. Recently the group have developed a novel bisulfite-free and direct base-resolution sequencing of DNA methylation, called TAPS (Nat. Biotechnol. 2019, 27, 424–429.). TAPS could replace bisulfite sequencing as the new standard in DNA epigenetic analysis and to have wide applications in academic research and clinical diagnostics, especially in sensitive low-input samples, such as circulating cell-free DNA epigenetic sequencing, long-read epigenetic sequencing and single-cell epigenetic sequencing.


The group will apply TAPS to the following research areas: cell-free DNA epigenetic sequencing for non-invasive early cancer detection; long-read epigenetic sequencing for cancer-associated viral methylome analysis; single-cell epigenetic sequencing to study tumour heterogeneity. This represents exciting opportunities for a postdoc to join the team to lead various applications with TAPS, to not only develop clinical diagnostics but also uncover new biological findings.


The successful candidate will be able to manage their own academic research and administrative activities, adapt and develop scientific techniques and contribute to ideas that will generate research income. You will carry out collaborative projects and represent the group at external meetings/seminars.


You must hold or be close to completion of a PhD (or equivalent) in molecular biology/biochemistry/genetics/chemistry or a related science degree.


This full-time position is fixed-term for 2 years in the first instance.


Further particulars, including details of how to apply, can be obtained from the document below. Applications for this vacancy should be made online and you will required to upload your CV and supporting statement as part of your application.


The closing date for this position will be 12.00 noon on Friday 5 July 2019.

Contact: Olivia Nash (01865 612682)