Postdoctoral Scientist in Human Immunology (CD4 Tfh Optimisation)

NDM Research Building, Old Road Campus, Headington, Oxford

Applications to be received by 12pm on Wednesday 20th of November 2019

Grade 7: £32,817 - £40,322 p.a.

We are seeking to appoint a Postdoctoral Scientist in Human Immunology to work as part of a small team in Oxford carrying out basic immunovirological research to inform the rational development of prophylactic HIV vaccines. This post is funded by the NIH as part of an international research consortium focusing on development of vaccines to elicit broadly neutralizing antibodies (bnAbs) to block infection with HIV. This is an exciting opportunity, entailing application of basic immunological research to inform vaccine design, and we are looking for an ambitious postdoctoral researcher to lead this component of our research.


The postholder will employ methods already established in the group for profiling B cell mediated epitope presentation and interrogating attributes of CD4 Tfh populations, and innovate in adapting and developing new techniques for characterisation of CD4 Tfh-B cell interactions. In addition to driving your own research you will work synergistically with other members of the team and with collaborators both in Oxford and in the USA, and will provide guidance to less experienced members of the group, including research assistants and PhD and project students.


You will report to Professor Persephone Borrow in conjunction with Professor (Emeritus) Sir Andrew McMichael. You will be expected to plan and independently carry out cutting edge laboratory research and develop and test hypotheses, analyse and interpret data, and develop ideas for future work. You will also contribute to the development of new research directions and develop ideas for generating additional research income (in liaison with the Group Head).


You will hold or be closer to completion of a relevant PhD/DPhil in immunology or a related biomedical science and have research experience in human cellular immunology. In addition you will have expertise in cellular immunological techniques including multiparameter flow cytometry and in vitro lymphocyte (co)culture. Pre- and/or postdoctoral research experience in human cellular immunology, with proven research skills in T cell immunity and/or antigen presentation


Experience with analysis of high-dimensional data (from flow cytometry and/or transcriptome studies) is also important, and knowledge of R highly desirable.


This full-time position is funded by the NIH, as part of the Consortium for HIV/AIDS Vaccine Development (CHAVD), and is offered on a fixed-term basis for 3 years in the first instance.


Further particulars, including details of how to apply, can be obtained from the document below. Applications for this vacancy should be made online and you will required to upload your CV and supporting statement as part of your application.


The closing date for this position will be 12.00 noon on Wednesday 20 November 2019.

Contact: Genevieve Moffa (01865 612892)