Postdoctoral Research Assistant in Cell Based High Throughput Screening

Target Discovery Institute (TDI), NDM Research Building, Headington, Oxford

Applications to be received by 12pm on Friday 29th of November 2019

Grade 7: £32,817 - £40,322 p.a.

This is an exciting opportunity to join the Target Discovery Institute working on a dynamic, exciting, multi-faceted, multi-site (MIT, Edinburgh and Oxford) research project focussed on discovering drugs to treat glioblastoma brain tumours. As Research Assistant you will be responsible for independently leading a research project developing and producing high throughput cell-based screens targeting glioblastoma stem cells across a range physiologically-relevant conditions. You will be responsible for all steps of development, production and analysis of the screens with an emphasis on high content imaging within TDI Cellular High Throughput Screening facility. You will also be responsible for designing further validation experiments to help prioritise potential drug candidates.


Your main responsibility will be to develop and produce a set of cell based high throughput assays targeting glioblastoma stem cells in the TDI Cellular Screening Facility as part of a large CRUK Brain Tumour funded project. You will manage your own academic research and administrative activities and develop new scientific techniques. You will independently test and develop a bench-top assay for small compound high throughput screening of glioblastoma stem cells.


You must hold or be close to completion of a PhD in cell biology, chemistry or a related field. You will have an excellent track record, professional experience and proven ability to independently lead a scientific research project from bench-top to completion and publication. The successful candidate should have considerable experience using high throughput liquid handling work stations and high content imagers.


Whilst the role is a Grade 7 position, we would be willing to consider candidates with potential but less experience who are seeking a development opportunity, for which an initial appointment would be at grade Grade 6 (£29,176 - £34,804 p.a.) with the responsibilities adjusted accordingly. This would be discussed with applicants at interview/appointment where appropriate.


This full-time position is fixed-term for 3 years in the first instance.


Further particulars, including details of how to apply, can be obtained from the document below. Applications for this vacancy should be made online and you will be required to upload a CV and supporting statement as part of your application.


The closing date for this post will be 12.00 noon on 29 November 2019.

Contact: Olivia Nash (01865 612682)