Postdoctoral Scientist-Integral Membrane Proteins Group 1

Nuffield Department of Medicine, Structural Genomics Consortium, Old Road Campus Research Building, Roosevelt Drive, Headington, Oxford and Boehringer Ingelheim, Biberach, Germany

Applications to be received by 12pm on Wednesday 27th of November 2019

Grade 7: £32,817 - £40,322 p.a.

We are seeking a Postdoctoral Scientist with membrane protein structural biology and electron microscopy experience to work as part of a collaboration between Professor Liz Carpenter’s group at the Structural Genomics Consortium in Oxford and the Structural Research Group of Boehringer Ingelheim in Biberach, Germany.

This position is funded by the Boehringer Ingelheim (BI) and will require the postholder to work 70% (183 days) from SGC labs in Oxford, UK and 30% (77 days) from the BI labs in Biberach, Germany.

This project aims to study the structures of complexes of human ion channels and solute carriers involved in genetic disease, using both electron cryo-microscopy and X-ray crystallography, combined with biophysical and biochemical methods to study function. This project will provide opportunities for training in cryo-EM, first hand insights into drug discovery, opportunities for international collaboration and high impact publications in the rapidly developing field of cryo-EM.

You will have a PhD or be close to completing your PhD in a relevant area of protein science and biochemistry and have proven experience in: membrane protein expression, purification, crystallisation and structure determination, preferably using cryo-EM. You will have excellent presentation and written communication skills and a proven record in the preparation of high quality research publications. You will be highly self-motivated, well-organised and flexible, with strong planning and problem solving skills with the ability to work independently, as part of a team and to collaborate with colleagues and external collaborators.

This post is fixed-term until 30 September 2022 and is funded by Boehringer Ingelheim (BI).

Applications for this vacancy are to be made online and you will be required to upload a CV and supporting statement as part of your online application. The supporting statement should explain how you meet the selection criteria for the post. Please quote reference 143819 on all correspondence.

Only applications received before 12.00 noon on 27 November 2019 will be considered.

Contact: Phillippa Wall (01865 617971)