Postdoctoral Scientist in Hypoxia Biology

Target Discovery Institute, NDM Research Building, Old Road Campus, Headington, Oxford, OX3 7FZ

Applications to be received by 12pm on Wednesday 22nd of July 2020

Grade 7: £32,817 - £40,322 per annum with discretionary range to £44,045

Applicants are invited for the position of Postdoctoral Scientist in Hypoxia Biology to work on the biology of syndromic kidney cancer within the Oxford Hypoxia Biology Laboratory, which is part of the Oxford Branch of the Ludwig Institute for Cancer Research.


You will join a team that is investigating familial kidney cancer syndromes; in particular von Hippel-Lindau (VHL) disease and hereditary leiomyomatosis and renal cancer (HLRCC), which are caused by mutations in the von Hippel-Lindau ubiquitin E3 ligase (pVHL) and Krebs Cycle enzyme fumarate hydratase (FH), respectively.


The work is problem orientated, and will encompass a range of techniques as scientifically appropriate, including the development, validation and analysis of cellular and animal models and the study of human material. Specific training and experience will be provided in both in situ analyses of tissue and in single-cell genomic analyses.


You will have a doctoral degree in a relevant discipline with experience in molecular and cellular biology. You are expected to have a methodical and careful approach to working in the laboratory independently. You will have an active interest in undertaking and supporting scientific research including attendance at relevant meetings and keeping up to date with the relevant scientific literature. Having the ability to work on several projects in parallel with excellent record keeping is also essential.


This position is fixed term until 31 December 2023 and funded by a Ludwig Core Award.


Applications for this vacancy are to be made online and you will be required to upload a supporting statement as part of your online application. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience.


Only applications received before 12.00, midday on Wednesday 22 July 2020 can be considered. Please quote reference, 146494 on all correspondence.

Contact: NDM Recruitment Team (01865 287870)