nalysis-ready datasets for insecticide resistance phenotype and genotype frequency in African malaria vectors
Moyes CL., Wiebe A., Gleave K., Trett A., Hancock PA., Padonou GG., Chouaïbou MS., Sovi A., Abuelmaali SA., Ochomo E., Antonio-Nkondjio C., Dengela D., Kawada H., Dabire RK., Donnelly MJ., Mbogo C., Fornadel C., Coleman M.
Abstract The impact of insecticide resistance in malaria vectors is poorly understood and quantified. Here a series of geospatial datasets for insecticide resistance in malaria vectors are provided, so that trends in resistance in time and space can be quantified, and the impact of resistance found in wild populations on malaria transmission in Africa can be assessed. Specifically, data have been collated and geopositioned for the prevalence of insecticide resistance, as measured by standard bioassays, in representative samples of individual species or species complexes. Data are provided for the Anopheles gambiae species complex, the Anopheles funestus subgroup, and for nine individual vector species. Data are also given for common genetic markers of resistance to support analyses of whether these markers can improve the ability to monitor resistance in low resource settings. Allele frequencies for known resistance-associated markers in the Voltage-gated sodium channel ( Vgsc ) are provided. In total, eight analysis-ready, standardised, geopositioned datasets encompassing over 20,000 African mosquito collections between 1957 and 2017 are released.