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Close analysis of intron phase - the position of introns within codons - is claimed to provide novel evidence supporting the view that introns predate the divergence of bacteria and eukaryotes and, via 'exon shuffling', played a crucial role in protein evolution. But just how compelling is this evidence?

Original publication

DOI

10.1016/s0960-9822(02)00535-3

Type

Journal article

Journal

Current biology : CB

Publication Date

05/1996

Volume

6

Pages

533 - 536

Addresses

Department of Genetics, Downing Street, Cambridge, CB2 3EH, UK.

Keywords

Animals, Humans, Codon, Evolution, Molecular, Species Specificity, Introns