Structure and mechanism of bactericidal mammalian perforin-2, an ancient agent of innate immunity
Ni T., Jiao F., Yu X., Aden S., Ginger L., Williams SI., Bai F., Pražák V., Karia D., Stansfeld P., Zhang P., Munson G., Anderluh G., Scheuring S., Gilbert RJC.
Bactericidal perforin-2 assembles an inactivated pre-pore complex and undergoes a 180° reconfiguration for membrane attack.