A Randomized Controlled Trial of Three- versus Five-Day Artemether-Lumefantrine Regimens for Treatment of Uncomplicated Plasmodium falciparum Malaria in Pregnancy in Africa
Onyamboko MA., Hoglund RM., Lee SJ., Kabedi C., Kayembe D., Badjanga BB., Turner GDH., Jackson NV., Tarning J., McGready R., Nosten F., White NJ., Day NPJ., Fanello C.
Artemether-lumefantrine antimalarial efficacy in pregnancy could be compromised by reduced drug exposure. Population-based simulations suggested that therapeutic efficacy would be improved if the treatment duration was increased.