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HIV infection affects up to 30% of children presenting with severe acute malnutrition (SAM) in Africa and is associated with increased mortality. Children with SAM are treated similarly regardless of HIV status, although mechanisms of nutritional recovery in HIV and/or SAM are not well understood. We performed a secondary analysis of a clinical trial and plasma proteomics data among children with complicated SAM in Kenya and Malawi. Compared to children with SAM without HIV (n = 113), HIV-infected children (n = 54) had evidence (false discovery rate (FDR) corrected p 

Original publication




Journal article


Scientific reports

Publication Date





Department of Gastroenterology, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium.


Humans, HIV Infections, Nutrition Therapy, Proteomics, Comorbidity, Nutritional Status, Child, Preschool, Infant, Kenya, Malawi, Female, Male, Lipid Metabolism, Stress, Physiological, Diet, High-Fat, Biomarkers, Severe Acute Malnutrition