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We investigated the value of susceptibility testing in predicting response in AIDS-associated cryptococcal meningitis using clinical isolates from a randomized controlled trial of antifungal treatment (amphotericin monotherapy, amphotericin with flucytosine, or amphotericin with fluconazole). We found no correlation between antifungal susceptibility and either early or late survival, or fungal clearance.

Original publication

DOI

10.1093/cid/ciaa1544

Type

Journal article

Journal

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Publication Date

10/2021

Volume

73

Pages

e2338 - e2341

Addresses

Guy's and St Thomas' NHS Trust, United Kingdom.