Heightened resistance to host type 1 interferons characterizes HIV-1 at transmission and after antiretroviral therapy interruption
Gondim MVP., Sherrill-Mix S., Bibollet-Ruche F., Russell RM., Trimboli S., Smith AG., Li Y., Liu W., Avitto AN., DeVoto JC., Connell J., Fenton-May AE., Pellegrino P., Williams I., Papasavvas E., Lorenzi JCC., Salantes DB., Mampe F., Monroy MA., Cohen YZ., Heath S., Saag MS., Montaner LJ., Collman RG., Siliciano JM., Siliciano RF., Plenderleith LJ., Sharp PM., Caskey M., Nussenzweig MC., Shaw GM., Borrow P., Bar KJ., Hahn BH.
Interferon-mediated pressures vary throughout HIV-1 infection but are the highest during viral rebound after treatment interruption.