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Talaromyces marneffei causes fatal invasive mycosis in Southeast Asia. Diagnosis by culture has limited sensitivity and can result in treatment delay. We describe the use of a novel Mp1p enzyme immunoassay (EIA) to identify blood culture-negative talaromycosis, subsequently confirmed by bone marrow cultures. This EIA has the potential to speed diagnosis, enabling early therapy initiation.

Original publication




Journal article


Open forum infectious diseases

Publication Date





University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.