The role and uses of antibodies in COVID-19 infections: a living review
Scourfield DO., Reed SG., Quastel M., Alderson J., Bart VMT., Teijeira Crespo A., Jones R., Pring E., Richter FC., Ahern DJ., Almuttaqi H., Alonzi DS., Alrubayyi A., Alsaleh G., Bart VMT., Batchelor V., Bayliss R., Berthold DL., Bezbradica JS., Bharuchq T., Borrmann H., Borsa M., Borst R., Brun J., Burnell SEA., Capitani L., Cavounidis A., Chapman L., Chauveau A., Cifuentes L., Codd AS., Compeer EB., Coveney C., Cross A., Danielli S., Davies LC., Dendrou CA., Dimonte S., Peter Durairaj RR., Dustin LB., Dyer A., Fielding C., Fischer F., Gallimore A., Galloway S., Gammage A., Gea-Mallorquí E., Godkin A., Hanna SJ., Heuberger C., Hulin-Curtis S., Issa F., Jones E., Jones R., Ladell K., Lauder SN., Liddiard K., Ligoxygakis P., Lu F., MacLachlan B., Maleki-Toyserkani S., Mann EH., Marzeda AM., James Matthews R., Mazet JM., Milicic A., Mitchell E., Moon O., Nguyen VD., O'Hanlon M., Eléonore Pavillet C., Peppa D., Pires A., Pring E., Quastel M., Reed S., Rehwinkel J., Richmond N., Richter FC., Robinson AJB., Rodrigues PRS., Sabberwal P., Sami A., Peres RS., Sattentau Q., Schonfeldova B., Scourfield DO., Selvakumar TA., Shepherd FR., Shorten C., Simon AK., Smith AL., Crespo AT., Tellier M., Thornton E., Uhl LFK., van Grinsven E., Wann AKT., Williams R., Wilson JD., Zhou D., Zhu Z., Burnell SEA.
<jats:title>Abstract</jats:title> <jats:p>Coronavirus disease 2019 has generated a rapidly evolving field of research, with the global scientific community striving for solutions to the current pandemic. Characterizing humoral responses towards SARS-CoV-2, as well as closely related strains, will help determine whether antibodies are central to infection control, and aid the design of therapeutics and vaccine candidates. This review outlines the major aspects of SARS-CoV-2-specific antibody research to date, with a focus on the various prophylactic and therapeutic uses of antibodies to alleviate disease in addition to the potential of cross-reactive therapies and the implications of long-term immunity.</jats:p>