Spatial modulation microscopy for real-time imaging of plasmonic nanoparticles and cells.
Fairbairn N., Light RA., Carter R., Fernandes R., Kanaras AG., Elliott TJ., Somekh MG., Pitter MC., Muskens OL.
Spatial modulation microscopy (SMM) is a technique originally developed for quantitative spectroscopy of individual nano-objects. Here, a parallel implementation of the SMM technique is demonstrated based on a line detector capable of demodulation at kHz frequencies. The capabilities of the imaging system are shown using an array of plasmonic nanoantennas and dendritic cells incubated with gold nanoparticles.